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68379 Ciz1

68379

Ciz1

CDKN1A interacting zinc finger protein 1

protein-coding

Mus musculus

基因描述

Type Description
Definition CDKN1A interacting zinc finger protein 1

研究结论

Date Results Publications
2019-06-22 11:24:00 CDKN1A interacting zinc finger protein 1 (Ciz1) knockout mice (Ciz1(DeltaE5/DeltaE5) ) lose residues encoded by exon 5 but may gain function from novel amino acid sequences. 30098009
2018-09-29 10:18:00 It plays a critical role in DNA replication and cell-cycle progression at the G1/S checkpoint. 29154038
2017-09-23 10:10:00 CIZ1 is recruited to Xi in response to expression of X inactive-specific transcript (Xist) RNA during the earliest stages of X inactivation in embryonic stem cells and is dependent on the C-terminal nuclear matrix anchor domain of CIZ1 and the E repeats of Xist CIZ1-null mice, although viable, display fully penetrant female-specific lymphoproliferative disorder. 28546514
2017-05-06 11:22:00 This study demonstrated that CIZ1 may be involved in the post-mitotic differentiation of neurons in response to external signals and changes in gene expression may compensate. 27163549
2016-01-16 11:12:00 CIZ1 is a kinase sensor that promotes initiation of DNA replication at low kinase levels, when in a hypophosphorylated state that is permissive for cyclin-A-CDK2 interaction and delivery to licensed origins. 25736292

名称对应

Type IDs
Synonymous 0610038H21Rik, 2900056O04Rik, LSFR1, ZNF356
Gene
UniProtKB-ID: Q3TXU6_MOUSE, A2AN61_MOUSE, Q3UUV0_MOUSE, Q8VEH2_MOUSE
UniprotKB: Q3TXU6, A2AN61, Q3UUV0, Q8VEH2
UniParc: UPI0000D77759, UPI0000028E06, UPI00005AD27D, UPI00005ABDD6
EMBL: AK159103, BC018483, AL808027, AK137961
Ensembl: ENSMUSG00000039205
KO: mmu:68379
Nucleutide sequences
EMBL-CDS: BAE34819.1, BAE23524.1, AAH18483.1
Ensembl_TRS: ENSMUST00000113331, ENSMUST00000113332, ENSMUST00000113338, ENSMUST00000113334, ENSMUST00000048964
Protein sequencees
Ensembl_PRO: ENSMUSP00000108957, ENSMUSP00000108958, ENSMUSP00000048428, ENSMUSP00000108964, ENSMUSP00000108960
RefSeq: XP_036018414.1, XP_030107885.1, NP_001239465.1, XP_030107876.1, NP_001239466.1, XP_006498342.1, XP_030107878.1, XP_030107881.1, XP_006498339.1, XP_006498348.1, NP_001239467.1, XP_030107887.1, XP_006498337.1, XP_036018412.1, XP_030107880.1, XP_006498346.1, XP_030107884.1, XP_036018415.1, XP_006498336.1, XP_006498334.1, XP_006498340.1, XP_036018416.1, XP_036018410.1, XP_006498341.1, XP_030107886.1, XP_006498344.1, XP_036018411.1, XP_006498343.1, XP_030107883.1, XP_006498338.1, XP_006498335.1, NP_082688.1, XP_030107879.1, XP_011237471.1, XP_036018413.1, XP_006498345.1, NP_001239463.1
Others
UniRef100: UniRef100_A2AN61, UniRef100_Q3UUV0, UniRef100_Q3TXU6, UniRef100_Q8VEH2
UniRef90: UniRef90_Q3TXU6
UniRef50: UniRef50_Q9ULV3
UniGene: Mm.170508

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