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68291 Mto1

68291

Mto1

mitochondrial tRNA translation optimization 1

protein-coding

Mus musculus

基因描述

Type Description
Definition mitochondrial tRNA translation optimization 1

研究结论

Date Results Publications
2016-02-06 10:28:00 MTO1 mediates tRNA modification and controls mitochondrial translation rate in a highly tissue-specific manner associated with tissue-specific oxidative phosphorylation defects. 25552653
2015-12-05 11:01:00 here described is an MTO1-deficient mouse model generated by gene trap mutagenesis that mirrors the human phenotype showing complex I defect and cardiomyopathy. 25506927
2010-01-21 00:00:00 These observations suggest that the mouse MTO1 is a structural and functional homolog of yeast MTO1, thereby playing a role in the mitochondrial tRNA modification and protein synthesis. 14522080

名称对应

Type IDs
Synonymous 2310039H01Rik, 5730419A02Rik
Gene
UniProtKB-ID: MTO1_MOUSE, G5E889_MOUSE
UniprotKB: Q923Z3, G5E889
UniParc: UPI0000028EA3, UPI0000023A57
EMBL: AF369902, AC158987, AK019088
Ensembl: ENSMUSG00000032342
KO: mmu:68291
Nucleutide sequences
EMBL-CDS: BAB31540.1, AAK63070.1
Ensembl_TRS: ENSMUST00000034896
Protein sequencees
Ensembl_PRO: ENSMUSP00000034896
RefSeq: NP_080934.2
Others
UniRef100: UniRef100_G5E889, UniRef100_Q923Z3
UniRef90: UniRef90_Q923Z3
UniRef50: UniRef50_Q9Y2Z2
UniGene: Mm.291779
CCDS: CCDS23363.1

全选

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研究热度

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