| Type | Description |
|---|---|
| Definition | SPT5 homolog, DSIF elongation factor subunit |
| Date | Results | Publications |
|---|---|---|
| 2021-04-17 13:14:00 | CRISPRi-mediated depletion of Spt4 and Spt5 reveals a role for DSIF in the control of HIV latency. | 33333262 |
| 2021-02-02 13:27:00 | SUPT5H Modulates PIN1 Expression, Inhibits Tumorigenicity, and Induces Apoptosis of Human Breast | 32961044 |
| 2020-02-22 12:07:00 | Poly(A) site-dependent deceleration caused by PNUTS-PP1 and Spt5 dephosphorylation is required to convert Pol II into a viable target for the Xrn2 terminator exonuclease, leading to transcription termination. | 31677974 |
| 2019-10-19 11:39:00 | the solution structures of the human Spt5 KOW4 and the C-terminal domain by nuclear magnetic resonance spectroscopy, are reported. | 30076330 |
| 2019-10-19 10:54:00 | Using mass spectrometry of both MYC and Pol II complexes, we show here that MYC controls the assembly of Pol II with a small set of transcription elongation factors that includes SPT5, a subunit of the elongation factor DSIF. MYC directly binds SPT5, recruits SPT5 to promoters, and enables the CDK7-dependent transfer of SPT5 onto Pol II | 30928206 |
| Type | IDs |
|---|---|
| Synonymous | SPT5, SPT5H, Tat-CT1 |
| Gene |
UniProtKB-ID:
SPT5H_HUMAN
UniprotKB:
O00267
UniParc:
UPI000006D81A,
UPI0000202334
EMBL:
Y12790,
BC024203,
U56402,
AF040253,
AB000516,
AB209257
Ensembl:
ENSG00000196235
KO:
hsa:6829
|
| Nucleutide sequences |
EMBL-CDS:
BAA24075.1,
CAA73326.1,
AAD02179.1,
AAH24203.1,
AAC51102.1,
BAD92494.1
Ensembl_TRS:
ENST00000599117,
ENST00000402194,
ENST00000598725,
ENST00000432763,
ENST00000359191
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000469090,
ENSP00000352117,
ENSP00000470252,
ENSP00000384505,
ENSP00000404029
RefSeq:
NP_001306920.1,
NP_001124297.1,
NP_001124296.1,
NP_003160.2,
XP_016882663.1,
NP_001306919.1,
NP_001104490.1
|
| Others |
UniRef100:
UniRef100_O00267
UniRef90:
UniRef90_O00267
UniRef50:
UniRef50_O00267
UniGene:
Hs.631604
CCDS:
CCDS12536.1,
CCDS46072.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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