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68275 Rpa1

68275

Rpa1

replication protein A1

protein-coding

Mus musculus

基因描述

Type Description
Definition replication protein A1

研究结论

Date Results Publications
2020-09-26 13:08:00 The Configuration of RPA, RAD51, and DMC1 Binding in Meiosis Reveals the Nature of Critical Recombination Intermediates. 32610038
2019-05-18 12:37:00 localization of the replication protein A (RPA) complex on the chromosome axes meiotic prophase in mouse spermatocytes, is reported. 30154456
2019-04-20 12:22:00 Using an inducible germline-specific inactivation strategy, we find that loss of RPA completely abrogates loading of RAD51/DMC1 recombinases to programmed meiotic DNA double strand breaks, thus blocking strand invasion required for chromosome pairing and synapsis. 30716097
2018-03-03 11:48:00 The recovery of abnormal phenotypes of mutant Ataxin-1 knock-in (Atxn1-KI) mice in the dendrite and spine morphology of Purkinje cells by AAV vector-mediated expression of RpA1 was reported. 28173122
2016-09-03 10:43:00 The authors establish that a second Dna2-Rpa interaction is mutually exclusive with Rpa-DNA interactions and mediates the displacement of Rpa from ssDNA. 26491943

名称对应

Type IDs
Synonymous 5031405K23Rik, 70kDa, AA589576, AW557552, RF-A, RP-A, Rpa
Gene
UniProtKB-ID: RFA1_MOUSE, Q3U8B3_MOUSE, Q5SWN2_MOUSE
UniprotKB: Q8VEE4, Q3U8B3, Q5SWN2
UniParc: UPI0000020AD9, UPI0000D8B60A, UPI00005ACBBB
EMBL: AK150785, AK165944, AK165316, AK148035, AK169599, AK167598, AK153144, BC019119, AK151590, AL603834, AK152296
Ensembl: ENSMUSG00000000751
KO: mmu:68275
Nucleutide sequences
EMBL-CDS: BAE41250.1, BAE38134.1, BAE30530.1, BAE29849.1, BAE39655.1, AAH19119.1, BAE31755.1, BAE28302.1, BAE38476.1, BAE31105.1
Ensembl_TRS: ENSMUST00000092907, ENSMUST00000000767
Protein sequencees
Ensembl_PRO: ENSMUSP00000090585, ENSMUSP00000000767
RefSeq: NP_001157695.1, XP_006534114.1, NP_080929.1
Others
UniRef100: UniRef100_Q5SWN2, UniRef100_Q3U8B3, UniRef100_Q8VEE4
UniRef90: UniRef90_Q8VEE4
UniRef50: UniRef50_P27694
UniGene: Mm.180734, Mm.472099
CCDS: CCDS25044.1

全选

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