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68273 Pomgnt1

68273

Pomgnt1

protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase

protein-coding

Mus musculus

基因描述

Type Description
Definition protein O-linked mannose beta 1,2-N-acetylglucosaminyltransferase

研究结论

Date Results Publications
2015-09-05 11:26:00 Findings suggest that PomGnT1 promotes GBM progression via activation of beta-catenin and may serve as a prognostic factor for glioma patient survival as well as a novel molecular target for anticancer therapy in malignant glioma. 25085363
2013-11-16 12:03:00 POMGnT1 gene knockout cause basement membrane disruptions in a mouse model of dystroglycanopathy. 23454088
2011-10-08 11:05:00 Results describe the effect of altered glycosylation of alpha-dystroglycan caused by inactivation of POMGnT1 in the retina. 21447391
2011-09-03 11:00:00 classical beta1,2-elongation and beta1,6-GlcNAc branching of O-mannose glycan structures are dependent upon the POMGnT1 enzyme and O-mannosylation is not limited solely to alpha-DG in the brain 21460210
2011-01-01 11:14:00 POMGnT1 knockout mice were viable but with reduced fertility and variable lifespan 20816176

名称对应

Type IDs
Synonymous 0610016I07Rik, 4930467B06Rik
Gene
UniProtKB-ID: PMGT1_MOUSE
UniprotKB: Q91X88
UniParc: UPI00000E745E, UPI0000194D3E, UPI0000001D04
EMBL: AB053221, AK019640, BC011201, AK015478, AL611947, AB053220, AK002638
Ensembl: ENSMUSG00000028700
KO: mmu:68273
Nucleutide sequences
EMBL-CDS: BAB29863.1, BAB31822.1, BAC55022.1, BAB22251.1, BAC55021.1, AAH11201.1
Ensembl_TRS: ENSMUST00000106496, ENSMUST00000106494, ENSMUST00000121052, ENSMUST00000120083, ENSMUST00000106498
Protein sequencees
Ensembl_PRO: ENSMUSP00000102103, ENSMUSP00000112911, ENSMUSP00000102105, ENSMUSP00000102107, ENSMUSP00000112751
RefSeq: NP_080927.1, NP_084062.2, NP_001277587.1
Others
UniRef100: UniRef100_Q91X88
UniRef90: UniRef90_Q8WZA1
UniRef50: UniRef50_Q8WZA1
UniGene: Mm.196045
CCDS: CCDS71450.1, CCDS18506.1, CCDS18507.1

全选

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