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6822 SULT2A1

6822

SULT2A1

sulfotransferase family 2A member 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition sulfotransferase family 2A member 1

研究结论

Date Results Publications
2019-01-26 11:52:00 Energy-dependent scoring of docking solutions identified the interaction as specific for the PAPSS2 and SULT2A1 isoforms 29743239
2018-12-01 11:45:00 Kinetic analyses showed further differential catalytic efficiency and substrate affinity of the SULT2A1 allozymes, in comparison with wild-type SULT2A1. These findings provided useful information concerning the effects of genetic polymorphisms on the sulfating activity of SULT2A1 allozymes. 29671343
2018-11-17 11:57:00 Polymorphisms of SULT2A1 gene is not associated with attention-deficit/hyperactivity disorder. 28367959
2018-11-10 10:54:00 Galeterone and abiraterone are novel inhibitors of DHEA sulfonation, as determined in enzymatic incubations containing human tissue cytosol (liver or intestinal) or human recombinant SULT enzyme (SULT2A1, SULT2B1b, or SULT1E1). 29436390
2018-10-27 10:56:00 nine human SULT2A1 allozymes plus the wild-type SULT2A1 were found to display differential sulfating activity toward DHEA and tibolone. Kinetic analysis revealed that different SULT2A1 allozymes exhibited differential substrate affinity and catalytic efficiency toward the two substrates tested. 29392568

名称对应

Type IDs
Synonymous DHEA-ST, DHEAS, HST, ST2, ST2A1, ST2A3, STD, hSTa
Gene
UniProtKB-ID: ST2A1_HUMAN, A8K015_HUMAN
UniprotKB: Q06520, A8K015
UniParc: UPI000013C7E8
EMBL: L36194, AK313415, L36192, L36193, X84816, S43859, U08024, X70222, L36191, U13059, U13058, U08025, L36195, L20000, U13057, BC020755, U13060, CH471126, L36196, U13061, AK289380, EU522670, U13056
Ensembl: ENSG00000105398
KO: hsa:6822
Nucleutide sequences
EMBL-CDS: AAH20755.1, AAB23169.2, AAA75491.1, CAA59274.1, AAA17749.1, AAA17750.1, AAA35758.1, AAC51353.1, CAA49755.1, EAW57516.1, BAG36209.1, BAF82069.1, ACB21041.1
Gene_ORFName: hCG_201431
Ensembl_TRS: ENST00000222002
Protein sequencees
Ensembl_PRO: ENSP00000222002
RefSeq: NP_003158.2
Others
UniRef100: UniRef100_Q06520
UniRef90: UniRef90_Q06520
UniRef50: UniRef50_Q06520
UniGene: Hs.515835
CCDS: CCDS12707.1

全选

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