Rnaseh2c - ribonuclease H2, subunit C-BMKCloudï½ç¾è¿å®¢äº

例如："NBL1", "4681", "drought"

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68209 Rnaseh2c

基因描述

Type	Description
Definition	ribonuclease H2, subunit C

研究结论

Date	Results	Publications
2014-06-07 12:53:00	Recent evidence gathered from ribonuclease H2 knock-out mice provides insight into the molecular mechanisms underlying Aicardi-Goutieres syndrome development and a potential role of DNA damage as a trigger of autoimmunity is discussed. [review]	23744109
2010-04-12 12:17:00	Data show that the interwoven architecture of RNase H2B and RNase H2C that interface with RNase H2A in a complex ideally suited for nucleic acid binding and hydrolysis coupled to protein-protein interaction motifs.	19923215

名称对应

Type	IDs
Synonymous	1500026D16Rik, AYP1
Gene	UniProtKB-ID: RNH2C_MOUSE UniprotKB: Q9CQ18 UniParc: UPI0000002FF6 EMBL: AK018776, BC024333, AF346604, AK011556 Ensembl: ENSMUSG00000024925 KO: mmu:68209
Nucleutide sequences	EMBL-CDS: AAH24333.1, BAB27694.1, BAB31401.1, AAO49175.1 Ensembl_TRS: ENSMUST00000025864
Protein sequencees	Ensembl_PRO: ENSMUSP00000025864 RefSeq: NP_080892.1
Others	UniRef100: UniRef100_Q9CQ18 UniRef90: UniRef90_Q9CQ18 UniRef50: UniRef50_Q9CQ18 UniGene: Mm.246200 CCDS: CCDS29471.1

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mRNA

Protein

UniprotKB

Description

Refseq

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Pubmed编号	文献信息	发表日期	相关基因
32325033	BraInMap Elucidates the Macromolecular Connectivity Landscape of Mammalian Brain. Cell Syst Reza Pourhaghighi , Peter E A Ash , Sadhna Phanse , Florian Goebels , Lucas Z M Hu , Siwei Chen , Yingying Zhang , Shayne D Wierbowski , Samantha Boudeau , Mohamed T Moutaoufik , Ramy H Malty , Edyta Malolepsza , Kalliopi Tsafou , Aparna Nathan , Graham Cromar , Hongbo Guo , Ali Al Abdullatif , Daniel J Apicco , Lindsay A Becker , Aaron D Gitler , Stefan M Pulst , Ahmed Youssef , Ryan Hekman , Pierre C Havugimana , Carl A White , Benjamin C Blum , Antonia Ratti , Camron D Bryant , John Parkinson , Kasper Lage , Mohan Babu , Haiyuan Yu , Gary D Bader , Benjamin Wolozin , Andrew Emili	2020-04-22	-
31125342	Aicardi-GoutiÃ¨res syndrome gene Rnaseh2c is a metastasis susceptibility gene in breast cancer. PLoS Genet. Sarah K Deasy , Ryo Uehara , Suman K Vodnala , Howard H Yang , Randall A Dass , Ying Hu , Maxwell P Lee , Robert J Crouch , Kent W Hunter	2019-05-01	-
23744109	Aicardi-GoutiÃ¨res syndrome: clues from the RNase H2 knock-out mouse. J. Mol. Med. BjÃ¶rn Rabe	2013-11-01	-
23603115	Ribonucleotides misincorporated into DNA act as strand-discrimination signals in eukaryotic mismatch repair. Mol. Cell Medini Manohar Ghodgaonkar , Federico Lazzaro , Maite Olivera-Pimentel , Mariela Artola-BorÃ¡n , Petr Cejka , Martin A Reijns , Andrew P Jackson , Paolo Plevani , Marco Muzi-Falconi , Josef Jiricny	2013-05-09	-
22802351	Mammalian RNase H2 removes ribonucleotides from DNA to maintain genome integrity. J. Exp. Med. Bjoern Hiller , Martin Achleitner , Silke Glage , Ronald Naumann , Rayk Behrendt , Axel Roers	2012-07-30	Cdkn1a, Phlda1, Zmat3, Rnaseh2b
22579044	Enzymatic removal of ribonucleotides from DNA is essential for mammalian genome integrity and development. Cell Martin A M Reijns , BjÃ¶rn Rabe , Rachel E Rigby , Pleasantine Mill , Katy R Astell , Laura A Lettice , Shelagh Boyle , Andrea Leitch , Margaret Keighren , Fiona Kilanowski , Paul S Devenney , David Sexton , Graeme Grimes , Ian J Holt , Robert E Hill , Martin S Taylor , Kirstie A Lawson , Julia R Dorin , Andrew P Jackson	2012-05-25	-
21873635	Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas	2011-09-01	-
21677750	A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley	2011-06-15	-
19923215	The structure of the mammalian RNase H2 complex provides insight into RNA.NA hybrid processing to prevent immune dysfunction. J Biol Chem Nadine M Shaban , Scott Harvey , Fred W Perrino , Thomas Hollis	2010-02-05	-
16141073	Antisense transcription in the mammalian transcriptome. Science S Katayama , Y Tomaru , T Kasukawa , K Waki , M Nakanishi , M Nakamura , H Nishida , C C Yap , M Suzuki , J Kawai , H Suzuki , P Carninci , Y Hayashizaki , C Wells , M Frith , T Ravasi , K C Pang , J Hallinan , J Mattick , D A Hume , L Lipovich , S Batalov , P G EngstrÃ¶m , Y Mizuno , M A Faghihi , A Sandelin , A M Chalk , S Mottagui-Tabar , Z Liang , B Lenhard , C Wahlestedt , RIKEN Genome Exploration Research Group , Genome Science Group (Genome Network Project Core Group) , FANTOM Consortium	2005-09-02	Gm14018, Gm14964, F630206G17Rik, Oog3, Notumos, Ldlrap1, Mdn1, Pydc3, 9330171B17Rik, Mfap1b, Tmsb15b2, Gm12802, E430020m11rik, Gm11335, Gm15772, Gm17762, A930017K11Rik, LOC100036513, Gata5os, Umad1, Gm16982, Gm9887, Gm9872, LOC100036530, Gm9934, Gm9913, Gm11149, BC028777, Gm13999, LOC100036540, Gm9744, Gm9983, D630002J18Rik, Gm16525, Gm11696, Dnajc3, 9430060I03Rik, Gm12359, 4921516A02Rik, Fam129c, Gm10589, Rsph3b, Rnaset2a, 5430403G19Rik, D030047H15Rik, Gm13274, B930046K06Rik, Gm10862, Gm10792, Gm10802, Gm10532, G730003C15Rik, Runx2os1, Gm15612, Gm10856, Gm10857, Gm10685, Gm10803, Gm10723, F630028O10Rik, Gm10836, Gm10405, Gm10513, Gm10609, F630201L12Rik, 4932427H20Rik, Zfp389, Gm10763, Gm10062, Gm10714, Gm10531, Gm10876, Gm10750, Gm10433, Gm10837, Gm10647, Gm10648, Gm10650, Gm10610, F830115B05Rik, Gm10473, Gm10614, Gm10286, G730046D07Rik, Gm10287, Gm10785, Gm10183, Gm10512, 1700061E17Rik, Gm44113, Gm10579, Gm10741, Gm10827, Gm10522, Gm10536, Gm15998, Faddos, D130050E23Rik, Gm10735

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