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6818 SULT1A3

6818

SULT1A3

sulfotransferase family 1A member 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition sulfotransferase family 1A member 3

研究结论

Date Results Publications
2020-03-14 12:04:00 The results obtained showed clearly the differential enzymatic characteristics of SULT1A3 allozymes in mediating the sulfation of phenylephrine and salbutamol. This information may contribute toward a better understanding of the pharmacokinetics of these two drugs in individuals with distinct SULT1A3 and/or SULT1A4 genotypes. 31145702
2019-03-16 12:58:00 In Alzheimer's disease patients, there was a significantly lower copy number in SULT1A3 genes compared to controls. 28374858
2019-03-02 12:33:00 Effects of human SULT1A3/SULT1A4 genetic polymorphisms on the sulfation of acetaminophen and opioid drugs by the cytosolic sulfotransferase SULT1A3 29705271
2018-06-09 11:53:00 analysis of the catechin-binding site of SULT1A3 28630292
2017-10-21 12:34:00 Our results implied that SULT1A3/4 exhibited bidirectional effect on tumor and normal hepatocytes and may thus provide a novel strategy for hepatocellular carcinoma clinical targeting. In addition, SULT1A3/4 re-expression could serve as a biomarker for hepatocellular carcinoma prognosis. 29025375

名称对应

Type IDs
Synonymous HAST, HAST3, M-PST, ST1A3, ST1A3/ST1A4, ST1A4, ST1A5, STM, TL-PST
Gene
UniProtKB-ID: ST1A3_HUMAN, ST1A4_HUMAN, Q1ET61_HUMAN
UniprotKB: P0DMM9, P0DMN0, Q1ET61
UniParc: UPI00006C1F0C, UPI0000046BED, UPI0000D7E6B6
EMBL: L34160, AK122707, BC132920, U20499, BC144354, AB111094, X84653, AK122733, AC133555, BC014471, BC078144, AK298073, U34199, AB111093, L19956, U08099, AC106782, BC171772, AB111099, BC132914, L25275, U37686, BC144355
Ensembl: ENSG00000261052, ENSG00000213648
KO: hsa:445329, hsa:6818
Nucleutide sequences
EMBL-CDS: AAA02943.1, BAE94928.1, AAA17723.1, AAC99987.1, AAH14471.1, AAA86536.1, AAA82126.1, BAC85507.1, CAA59146.1, AAA64490.1, AAH78144.1, BAG60362.1, AAA36523.1, BAE94933.1, AAI71772.1, BAG53679.1, AAI32921.1, AAI44355.1, AAI44356.1, AAI32915.1, BAE94927.1
Ensembl_TRS: ENST00000563322, ENST00000338971, ENST00000395138, ENST00000360423
Protein sequencees
Ensembl_PRO: ENSP00000454518, ENSP00000378570, ENSP00000343645, ENSP00000353600
RefSeq: NP_808220.1
Others
UniRef100: UniRef100_P0DMM9
UniRef90: UniRef90_P0DMM9
UniRef50: UniRef50_P0DMM9
UniGene: Hs.460558
CCDS: CCDS32427.1, CCDS10674.1, CCDS32427.1

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