| Type | Description |
|---|---|
| Definition | wntless WNT ligand secretion mediator |
| Date | Results | Publications |
|---|---|---|
| 2020-06-27 10:56:00 | Data show that epithelial Wntless was required for the growth and differentiation of small intestinal organoids but not in live animals. | 31547988 |
| 2019-09-14 11:44:00 | Deletion of WLS in peritubular myoid cells is not essential for male fertility in mice. | 29693774 |
| 2019-01-12 11:15:00 | Data show that Shh-Cre-mediated deletion of Wntless, the Wnt cargo protein, in mouse posterior limb mesenchyme causes bone syndactyly of the 3rd and 4th digits, resembling the human Malik-Percin type . Wntless(Shh-Cre) limbs displayed altered expression of hedgehog pathway genes and impaired noncanonical Wnt signaling activity. | 29292497 |
| 2018-09-22 12:21:00 | WLS role in the principal cells of the caput epididymidis during sperm maturation | 29152689 |
| 2018-01-13 13:34:00 | Wntless-deficient macrophages presented a unique subset of M2-like macrophages with anti-inflammatory, reparative, and angiogenic properties. Serial echocardiography studies revealed that mice lacking macrophage Wnt secretion showed improved function and less remodeling 30 days after myocardial infarction. | 28062479 |
| Type | IDs |
|---|---|
| Synonymous | 5031439A09Rik, AI173978, AI987742, EVI, Gpr177 |
| Gene |
UniProtKB-ID:
WLS_MOUSE
UniprotKB:
Q6DID7
UniParc:
UPI00001F0175,
UPI0000022DF0
EMBL:
AK019886,
AK049842,
BC075615,
AK044810,
AK029053,
BC018381,
AK029104,
AK159207,
AK077407
Ensembl:
ENSMUSG00000028173
KO:
mmu:68151
|
| Nucleutide sequences |
EMBL-CDS:
BAC26266.1,
BAC32102.1,
BAC33950.1,
BAB31904.1,
BAC36788.1,
BAE34898.1,
BAC26300.1,
AAH18381.1,
AAH75615.1
Ensembl_TRS:
ENSMUST00000068952,
ENSMUST00000198878
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000143475,
ENSMUSP00000067898
RefSeq:
NP_001343278.1,
NP_080858.3,
NP_001343279.1
|
| Others |
UniRef100:
UniRef100_Q6DID7
UniRef90:
UniRef90_Q5T9L3
UniRef50:
UniRef50_Q5T9L3
UniGene:
Mm.6766
CCDS:
CCDS38684.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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