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6815 STYX

6815

STYX

serine/threonine/tyrosine interacting protein

protein-coding

Homo sapiens

基因描述

Type Description
Definition serine/threonine/tyrosine interacting protein

研究结论

Date Results Publications
2021-04-03 13:30:00 STYX/FBXW7 axis participates in the development of endometrial cancer cell via Notch-mTOR signaling pathway. 32239181
2020-04-11 11:46:00 STYX bound to the F-box and WD repeat domain-containing7 (FBXW7) protein and inhibited its function. Co-regulation of STYX and FBXW7 expression reversed the biological changes mediated by regulation of STYX expression alone in CRC cells. 30981757
2017-07-08 10:46:00 The authors show that STYX binds to the F-box domain of FBXW7 and disables its recruitment into the SCF ubiquitin ligase complex. 28007894
2017-05-06 10:59:00 Results suggest that STYX is a pseudophosphatase that uses the 'competitor' and 'anchor' mode of action to exert its biologic roles. [review] 28408485
2013-11-30 10:47:00 results identify STYX as an important regulator of ERK1/2 signaling critical for cell migration 23847209

名称对应

Type IDs
Gene
UniProtKB-ID: STYX_HUMAN, A0A024R641_HUMAN
UniprotKB: Q8WUJ0, A0A024R641
UniParc: UPI00000434EF
EMBL: BC020265, CH471078, BC146998, BC146995, CH471061, U87169, AK098195
Ensembl: ENSG00000198252
KO: hsa:6815
Nucleutide sequences
EMBL-CDS: AAI46999.1, EAW65644.1, AAB47561.1, AAH20265.1, AAI46996.1, EAW80612.1, BAC05259.1, EAW65641.1, EAW80613.1
Gene_ORFName: hCG_2028303
Ensembl_TRS: ENST00000354586, ENST00000442123
Protein sequencees
Ensembl_PRO: ENSP00000403214, ENSP00000346599
RefSeq: XP_011535411.1, NP_001124173.1, XP_011535410.1, NP_660294.1
Others
UniRef100: UniRef100_Q8WUJ0
UniRef90: UniRef90_Q8WUJ0
UniRef50: UniRef50_Q8WUJ0
UniGene: Hs.364980
CCDS: CCDS9711.1

全选

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