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6814 STXBP3

6814

STXBP3

syntaxin binding protein 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition syntaxin binding protein 3

研究结论

Date Results Publications
2019-02-09 12:21:00 Pancreatic acini from Munc18c-depleted mice (Munc18c(+/-)) and human pancreas (lenti-Munc18c-shRNA-treated) exhibit normal apical exocytosis of zymogen granules (ZGs) in response to physiologic stimulation with the intestinal hormone cholecystokinin (CCK-8). 29284677
2018-03-31 11:22:00 PP2B-Aalpha-Munc18c complex supports agonist-induced VWF secretion by HUVECs. 28294518
2017-10-21 11:59:00 Data suggest MUNC18C is required for STX4-mediated invadopodium formation and tumor invasion of extracellular matrix; N-terminal STX4 fragment binds to MUNC18C and inhibits interactions of STX4 with synaptosome-associated protein 23 (SNAP23) and vesicle-associated membrane protein 2 (VAMP2). Fibrosarcoma/adenocarcinoma cell lines were used in these studies. (MUNC18C = syntaxin binding protein MUNC18C; STX4 = syntaxin 4) 28798239
2015-03-21 10:12:00 In vitro interaction assays indicated that Doc2b is required to bridge the interaction between Munc18c and Munc18-1 in the macromolecular complex; Munc18c and Munc18-1 failed to associate in the absence of Doc2b 25190515
2013-12-28 11:19:00 Munc18c gene expression in human adipose tissue is down-regulated in morbid obesity. 23700440

名称对应

Type IDs
Synonymous MUNC18-3, MUNC18C, PSP, UNC-18C
Gene
UniProtKB-ID: STXB3_HUMAN
UniprotKB: O00186
UniParc: UPI000000DC53
EMBL: AK291322, BC038099, AK290134, AF032922, CH471122, BC047764, AL449266, AK223170, AL591719, AK312910, D63506
Ensembl: ENSG00000116266
KO: hsa:6814
Nucleutide sequences
EMBL-CDS: AAH38099.1, AAC69606.1, BAF82823.1, BAA19482.1, EAW56330.1, BAD96890.1, AAH47764.1, BAG35756.1, BAF84011.1
Ensembl_TRS: ENST00000370008
Protein sequencees
Ensembl_PRO: ENSP00000359025
RefSeq: NP_009200.2
Others
UniRef100: UniRef100_O00186
UniRef90: UniRef90_O00186
UniRef50: UniRef50_Q60770
UniGene: Hs.530436
CCDS: CCDS790.1

全选

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研究热度

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