| Type | Description |
|---|---|
| Definition | UPF3 regulator of nonsense transcripts homolog B (yeast) |
| Date | Results | Publications |
|---|---|---|
| 2021-02-27 13:45:00 | The role of the NMD factor UPF3B in olfactory sensory neurons. | 32773035 |
| 2019-08-17 10:51:00 | Study reports the generation and characterization of mice harboring a null Upf3b allele. These Upf3b-null mice exhibit deficits in fear-conditioned learning, but not spatial learning. Upf3b-null mice also have a profound defect in prepulse inhibition. Cortical pyramidal neurons from Upf3b-null mice display deficient dendritic spine maturation in vivo. | 28948974 |
| 2016-09-03 12:18:00 | Analysis revealed that UPF3A is a broadly acting nonsense-mediated RNA decay inhibitor. This discovery implies that UPF3A and UPF3B do not primarily work in a complementary or redundant manner as previously supposed; instead, they oppose each other, allowing this paralog pair to serve as a molecular rheostat to modulate the level of gene expression during development. | 27040500 |
| 2014-06-21 11:01:00 | Evidence suggests Upf3b-dependent nonsense-mediated mRNA decay is regulated at multiple levels during development including regulation of expression and sub-cellular localization of Upf3b. | 23821644 |
| Type | IDs |
|---|---|
| Synonymous | 5730594O13Rik, AI317193, AW541158, RENT3B, UPF3X |
| Gene |
UniProtKB-ID:
Q3ULL6_MOUSE,
Q80UI8_MOUSE
UniprotKB:
Q3ULL6,
Q80UI8
UniParc:
UPI000000BB5B,
UPI00001C63FD
EMBL:
AK145431,
AL451076,
BC047049
Ensembl:
ENSMUSG00000036572
KO:
mmu:68134
|
| Nucleutide sequences |
EMBL-CDS:
BAE26432.1,
AAH47049.1
Ensembl_TRS:
ENSMUST00000076265
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000075614
RefSeq:
XP_036017977.1,
NP_080849.1,
XP_036017978.1,
XP_006541457.1,
XP_036017976.1
|
| Others |
UniRef100:
UniRef100_Q3ULL6
UniRef90:
UniRef90_Q9CS15
UniRef50:
UniRef50_P62891
UniGene:
Mm.271160
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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