| Type | Description |
|---|---|
| Definition | syntaxin 4 |
| Date | Results | Publications |
|---|---|---|
| 2019-08-17 12:30:00 | Nitric Oxide Generated by Tumor-Associated Macrophages Is Responsible for Cancer Resistance to Cisplatin and Correlated With Syntaxin 4 and Acid Sphingomyelinase Inhibition. | 29896202 |
| 2018-08-18 11:15:00 | these results indicate that the activation of beta-ARs induces secretory granules and cell membrane fusion via the interaction of VAMP-2 and syntaxin-4 in a and F-actin-dependent manner in human submandibular gland. Up-regulated beta-ARs might participate in altering protein secretion in transplanted submandibular gland by promoting the interaction of VAMP-2 with syntaxin-4. | 29358308 |
| 2018-06-09 12:00:00 | Confocal immunofluorescence microscopy revealed a colocalization of syntaxin 4 with a MVB-specific marker, exosomes and hepatitis C virus (HCV) core, which suggests a fraction of syntaxin 4 is associated with exosomes loaded with HCV. Altogether, it is assumed that syntaxin 4 is a novel essential cellular factor for the release of HCV. | 28624237 |
| 2018-03-10 10:43:00 | The authors found that activation of dendritic cells by bacterial lipopolysaccharide leads to increased Forster resonance energy transfer-fluorescence of fluorescently labeled syntaxin 4 with VAMP3 specifically at the plasma membrane, indicating increased SNARE complex formation, whereas FRET with other tested SNAREs was unaltered. | 28524818 |
| 2017-10-21 11:59:00 | Data suggest MUNC18C is required for STX4-mediated invadopodium formation and tumor invasion of extracellular matrix; N-terminal STX4 fragment binds to MUNC18C and inhibits interactions of STX4 with synaptosome-associated protein 23 (SNAP23) and vesicle-associated membrane protein 2 (VAMP2). Fibrosarcoma/adenocarcinoma cell lines were used in these studies. (MUNC18C = syntaxin binding protein MUNC18C; STX4 = syntaxin 4) | 28798239 |
| Type | IDs |
|---|---|
| Synonymous | STX4A, p35-2 |
| Gene |
UniProtKB-ID:
STX4_HUMAN,
B7Z425_HUMAN
UniprotKB:
Q12846,
B7Z425
UniParc:
UPI000013F676,
UPI0000136162,
UPI00003E28D4
EMBL:
AF318489,
AJ000541,
BT007326,
U07158,
X85784,
AF026007,
CR541806,
BC002436,
AK091833,
AC135050,
AK296652,
AK315716,
CH471192
Ensembl:
ENSG00000103496
KO:
hsa:6810
|
| Nucleutide sequences |
EMBL-CDS:
AAP35990.1,
AAA20967.1,
EAW52177.1,
AAB88810.1,
CAA59769.1,
AAH02436.1,
BAG52424.1,
CAG46605.1,
EAW52176.1,
AAG40313.1,
BAG38075.1,
CAA04174.1,
EAW52175.1,
BAH12411.1
Gene_ORFName:
hCG_21149
Ensembl_TRS:
ENST00000313843,
ENST00000394998
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000317714,
ENSP00000378447
RefSeq:
XP_005255578.1,
NP_004595.2,
NP_001259025.1,
NP_001259024.1
|
| Others |
UniRef100:
UniRef100_Q12846
UniRef90:
UniRef90_Q12846
UniRef50:
UniRef50_Q12846
UniGene:
Hs.83734
CCDS:
CCDS10700.1,
CCDS61916.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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