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6809 STX3

6809

STX3

syntaxin 3

protein-coding

Homo sapiens

基因描述

Type Description
Definition syntaxin 3

研究结论

Date Results Publications
2020-09-05 13:52:00 Interaction networks of Weibel-Palade body regulators syntaxin-3 and syntaxin binding protein 5 in endothelial cells. 31201948
2019-07-20 12:04:00 Syntaxin-3 is a novel Weibel-Palade body-associated SNARE protein that controls WPB von Willebrand factor exocytosis. 29880488
2018-12-22 10:13:00 Stx3S is differentially expressed in normal human tissues, during epithelial cell polarization, and in breast cancer versus normal breast tissue. Inhibition of endogenous Stx3S expression alters the expression of cancer-associated genes and promotes cell proliferation. 29475951
2018-07-14 11:30:00 mechanism study shows that STX3 binds to PTEN and increases PTEN ubiquitination and degradation, thus leading to activation of the PI3K-Akt-mTOR signaling. Therefore, STX3 promotes the growth of breast cancer cells by regulating the PTEN-PI3K-Akt-mTOR signaling. 29408595
2016-05-14 11:43:00 we report for the first time a missense mutation of a novel lens specific gene STX3 in a phenotype associating autosomal recessive congenital cataract and intellectual disability. 25358429

名称对应

Type IDs
Synonymous STX3A
Gene
UniProtKB-ID: STX3_HUMAN, Q53YE2_HUMAN
UniprotKB: Q13277, Q53YE2
UniParc: UPI000002B456, UPI000016786E, UPI00001FA7E0
EMBL: AK297419, AJ002077, CH471076, AP000640, AJ002076, AK290251, X90581, BT006666, U32315, AK312909, AK125660, BC007429, BC007405
Ensembl: ENSG00000166900
KO: hsa:6809
Nucleutide sequences
EMBL-CDS: CAA62209.1, CAA05175.1, AAH07429.1, CAA05176.1, AAA75303.1, EAW73854.1, AAH07405.1, BAG59852.1, BAG35755.1, BAG54232.1, EAW73855.1, AAP35312.1, BAF82940.1
Gene_ORFName: hCG_40920
Ensembl_TRS: ENST00000337979, ENST00000529177
Protein sequencees
Ensembl_PRO: ENSP00000433248, ENSP00000338562
RefSeq: XP_016873678.1, XP_016873680.1, XP_016873685.1, XP_005274255.1, XP_016873684.1, XP_005274257.1, XP_016873682.1, XP_016873683.1, NP_004168.1, XP_016873677.1, NP_001171511.1, XP_016873681.1, XP_011543523.1, XP_016873679.1, XP_005274252.1
Others
UniRef100: UniRef100_Q13277
UniRef90: UniRef90_Q13277
UniRef50: UniRef50_P32856
UniGene: Hs.180711
CCDS: CCDS7975.1, CCDS53637.1

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