| Type | Description |
|---|---|
| Definition | neuromedin B |
| Date | Results | Publications |
|---|---|---|
| 2020-02-08 10:48:00 | NMB-treated mice were less susceptible to virus challenge, as evidenced by increased survival, increased body weight, and decreased viral NP expression compared with the control animals. As expected, opposing effects were observed in the NMBR antagonist-treated cells and mice, which further confirmed the effects of NMB. | 31601264 |
| 2019-07-27 10:55:00 | Study shows that itch deficits in mice lacking NMB or GRP are non-redundant and Nmb/Grp double KO (DKO) mice displayed additive deficits. Furthermore, both Nmb/Grp and Nmbr/Grpr DKO mice responded normally to a wide array of noxious stimuli. NMB and GRP may transmit discrete itch information and NMBR neurons are an integral part of neural circuits for itch in the spinal cord. | 29133874 |
| 2017-10-21 12:24:00 | NMB or NMBR silencing inhibited M-CSF/c-Fms-mediated downstream signaling pathways like activation of ERK and Akt and induction of D-type cyclins, cyclin D1 and D2. | 28780306 |
| 2014-08-30 11:54:00 | Data show that neuromedin B (NMB) expression was higher in the melanocortin 2 receptor MC2R(-/-) than in the wild-type (WT) mice. | 24742195 |
| 2013-02-16 11:00:00 | The majority of dorsal spinal cord Grp is synthesized locally in dorsal spinal cord neurons while Nmb is highly expressed in pain- and itch-sensing dorsal root ganglion neurons. | 22776446 |
| Type | IDs |
|---|---|
| Synonymous | 3110023K12Rik |
| Gene |
UniProtKB-ID:
NMB_MOUSE,
D3Z621_MOUSE
UniprotKB:
Q9CR53,
D3Z621
UniParc:
UPI000173A796,
UPI0000001A50
EMBL:
BC028490,
AK014077,
AC123744,
AK011929
Ensembl:
ENSMUSG00000025723
KO:
mmu:68039
|
| Nucleutide sequences |
EMBL-CDS:
AAH28490.1,
BAB27922.1,
BAB29144.1
Ensembl_TRS:
ENSMUST00000026817,
ENSMUST00000119428
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000026817,
ENSMUSP00000113407
RefSeq:
NP_001278209.1,
NP_080799.1
|
| Others |
UniRef100:
UniRef100_D3Z621,
UniRef100_Q9CR53
UniRef90:
UniRef90_Q9CR53
UniRef50:
UniRef50_Q9CR53
UniGene:
Mm.22246
CCDS:
CCDS21400.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员