| Type | Description |
|---|---|
| Definition | caveolae associated 4 |
| Date | Results | Publications |
|---|---|---|
| 2021-01-09 13:29:00 | Systems Network Genomic Analysis Reveals Cardioprotective Effect of MURC/Cavin-4 Deletion Against | 31364493 |
| 2018-09-08 10:42:00 | MURC binds to Cav1 and inhibits the association of Cav1 with the active form of Galpha13, resulting in the facilitated association of the active form of Galpha13 with p115RhoGEF. These results reveal that MURC has a function in the development of pulmonary hypertension through modulating Rho/ROCK signaling. | 27546070 |
| 2017-07-08 10:06:00 | The MURC/Cavin-4 in vascular smooth muscle cells modulates abdominal aortic aneurysm (AAA) progression at the early stage via the activation of JNK and MMP-9. MURC/Cavin-4 is a potential therapeutic target against AAA progression. | 28433630 |
| 2014-05-10 10:05:00 | MURC/Cavin-4 facilitates recruitment of ERK to caveolae and concentric cardiac hypertrophy induced by alpha1-adrenergic receptors. | 24567387 |
| 2010-01-21 00:00:00 | Data show that MURC/Cavin-4 forms a multiprotein complex that associates with caveolae, and identify Cavin-4 as a novel muscle disease candidate caveolar protein. | 19546242 |
| Type | IDs |
|---|---|
| Synonymous | 2310039E09Rik, Murc |
| Gene |
UniProtKB-ID:
CAVN4_MOUSE
UniprotKB:
A2AMM0
UniParc:
UPI00001F0D0A
EMBL:
CH466565,
AK009073,
AK009691,
AL807771,
BC089601,
EU487254
Ensembl:
ENSMUSG00000028348
KO:
mmu:68016
|
| Nucleutide sequences |
EMBL-CDS:
ACA62936.1,
BAB26442.1,
BAB26056.1,
EDL02328.1,
AAH89601.1
Ensembl_TRS:
ENSMUST00000030033
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000030033
RefSeq:
NP_080785.2
|
| Others |
UniRef100:
UniRef100_A2AMM0
UniRef90:
UniRef90_A2AMM0
UniRef50:
UniRef50_A2AMM0
UniGene:
Mm.133444
CCDS:
CCDS18169.2
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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