| Type | Description |
|---|---|
| Definition | TNF receptor-associated protein 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-10-21 12:47:00 | show that TRAP1 could protect the mitochondrial structure in renal tubular epithelial cells; maintain the levels of mitochondrial membrane potential, ATP, and mitochondrial DNA copy number | 28710113 |
| 2017-05-27 10:49:00 | TRAP1 increases cell proliferation, reduces apoptosis, and promotes cell invasion without changes in mitochondrial bioenergetics. Therefore, TRAP1 is a driver of prostate cancer in vivo and an "actionable" therapeutic target. | 27754870 |
| 2016-09-17 10:12:00 | Data show that the overexpression of heat shock protein 75 (Hsp75) decreased neural stem cells (NSCs) apoptosis and preserved mitochondrial membrane potential. | 26500047 |
| 2015-08-29 11:32:00 | TRAP-1-/- mice are viable and show reduced incidence of age-associated pathologies. Loss of TRAP-1 upregulates oxidative phosphorylation and glycolysis transcriptomes. | 25088416 |
| 2014-08-30 10:41:00 | overexpression of TRAP1 leads to mitochondrial aberrations, including an increase in basal levels and decrease in mitochondrial biogenesis, together with a decrease in peroxisome proliferator-activated receptor gamma coactivator-1alpha mRNA levels | 24286320 |
| Type | IDs |
|---|---|
| Synonymous | 2410002K23Rik, HSP75 |
| Gene |
UniProtKB-ID:
TRAP1_MOUSE
UniprotKB:
Q9CQN1
UniParc:
UPI00000019BD
EMBL:
AK088471,
AK010341,
BC022912,
AK002409
Ensembl:
ENSMUSG00000005981
KO:
mmu:68015
|
| Nucleutide sequences |
EMBL-CDS:
AAH22912.1,
BAB26865.1,
BAC40374.1,
BAB22078.1
Ensembl_TRS:
ENSMUST00000006137
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000006137
RefSeq:
NP_080784.1
|
| Others |
UniRef100:
UniRef100_Q9CQN1
UniRef90:
UniRef90_Q5XHZ0
UniRef50:
UniRef50_Q5XHZ0
UniGene:
Mm.123366
CCDS:
CCDS27914.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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