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67981 Hormad1

67981

Hormad1

HORMA domain containing 1

protein-coding

Mus musculus

基因描述

Type Description
Definition HORMA domain containing 1

研究结论

Date Results Publications
2021-04-17 13:13:00 Aberrantly expressed HORMAD1 disrupts nuclear localization of MCM8-MCM9 complex and compromises DNA mismatch repair in cancer cells. 32647118
2020-11-21 13:18:00 Meiotic cohesins mediate initial loading of HORMAD1 to the chromosomes and coordinate SC formation during meiotic prophase. 32931493
2020-02-29 11:30:00 We identify, de novo, DNA sequence motifs associated with individual components that define temporally varying modes of gene expression control. Analysis of SDA components also led us to identify a rare population of macrophages within the seminiferous tubules of Mlh3(-/-) and Hormad1(-/-) mice, an area typically associated with immune privilege 31237565
2018-08-18 11:52:00 Exogenous DSBs recruit the meiosis-specific homologous recombination repair machinery, are translocated to the axial elements, contribute to homology recognition, and that their repair is modulated by HORMAD1. 29414051
2017-05-27 11:53:00 that HORMAD1-IHO1 interaction provides a mechanism for the selective promotion of DNA double-strand break formation along unsynapsed chromosome axes 27723721

名称对应

Type IDs
Synonymous 4921522K05Rik, Nohma
Gene
UniProtKB-ID: HORM1_MOUSE
UniprotKB: Q9D5T7
UniParc: UPI0000027092, UPI00000E7049
EMBL: BC051129, AY626343, AK014945, AK163995, AK016743, AK016324, AY634284
Ensembl: ENSMUSG00000028109
KO: mmu:67981
Nucleutide sequences
EMBL-CDS: AAT47126.1, AAH51129.1, AAT45739.1, BAE37577.1, BAB29633.1, BAB30195.1, BAB30406.1
Ensembl_TRS: ENSMUST00000171191, ENSMUST00000029754, ENSMUST00000107154, ENSMUST00000090797
Protein sequencees
Ensembl_PRO: ENSMUSP00000088303, ENSMUSP00000029754, ENSMUSP00000127180, ENSMUSP00000102772
RefSeq: NP_001276461.1, NP_001360815.1, NP_080765.1, NP_001276463.1, NP_001276466.1
Others
UniRef100: UniRef100_Q9D5T7
UniRef90: UniRef90_Q9D5T7
UniRef50: UniRef50_Q9D5T7
UniGene: Mm.179050
CCDS: CCDS71292.1, CCDS38547.1

全选

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