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67952 Tomm20

67952

Tomm20

translocase of outer mitochondrial membrane 20

protein-coding

Mus musculus

基因描述

Type Description
Definition translocase of outer mitochondrial membrane 20

研究结论

Date Results Publications
2020-01-11 11:32:00 Mitochondrial reactive oxygen species increase protein abundance of mitochondrial SGK1, which leads to a rise of mitochondrial Tom20. 31177508
2019-12-14 11:08:00 While TOM20 overexpression exacerbated neurodegeneration in Parkinson's disease model, in both substantia nigra pars compacta and striatum, overexpression of TIM23 partially protected dopaminergic neurons in the substantia nigra pars compacta. 30405116
2019-07-06 12:00:00 TOM70, but not TOM20, clusters in distinct OMM foci, frequently overlapping with sites in which the endoplasmic reticulum (ER) contacts mitochondria. Functionally, TOM70 depletion specifically impairs inositol trisphosphates (IP3)-linked ER to mitochondria Ca(2+) transfer. This phenomenon is dependent on the capacity of TOM70 to interact with IP3-receptors and favor their functional recruitment close to mitochondria. 29395920

名称对应

Type IDs
Synonymous 1810060K07Rik, BB284719, Gm19268, MAS20, MOM19, TOM20, mKIAA0016
Gene
UniProtKB-ID: TOM20_MOUSE, Q4KL41_MOUSE
UniprotKB: Q9DCC8, Q4KL41
UniParc: UPI00000238D8
EMBL: AK141367, BC099449, AK160168, AK002902, BC002087
Ensembl: ENSMUSG00000093904
KO: mmu:67952
Nucleutide sequences
EMBL-CDS: AAH02087.1, BAB22444.1, BAE24663.1, AAH99449.1, BAE35669.1
Ensembl_TRS: ENSMUST00000179857
Protein sequencees
Ensembl_PRO: ENSMUSP00000136493
RefSeq: NP_077176.1
Others
UniRef100: UniRef100_Q9DCC8
UniRef90: UniRef90_Q15388
UniRef50: UniRef50_Q15388
UniGene: Mm.6932, Mm.372086, Mm.489811
CCDS: CCDS22786.1

全选

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研究热度

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