| Type | Description |
|---|---|
| Definition | mesoderm development LRP chaperone |
| Date | Results | Publications |
|---|---|---|
| 2014-01-18 11:10:00 | Mescd2 binds to Lrp4 and regulates Lrp4 surface expression in myotubes. | 24140340 |
| 2013-08-31 12:09:00 | Mesd C-terminal region constitutes the major LRP5/6-binding domain, and that Mesd protein and its C-terminal region peptide have a potential therapeutic value in cancer | 23469146 |
| 2011-07-02 10:03:00 | The region 45-184 of MESD is essential and sufficient to act as a molecular chaperone for the low-density lipoprotein receptor (LDLR) family. | 21397185 |
| 2011-03-22 06:00:00 | Secondary structure prediction using chemical shift data indicates that MESD(12-155) contains four a-helices and five b-sheets. | 19636811 |
| 2011-03-22 06:00:00 | Mesd not only blocks binding of Dickkopf (DKK)-1 and sclerostin proteins to low-density lipoprotein receptor-related protein (LRP)5 and LRP6 but also inhibits Wnt/beta-catenin signaling in LRP5- or LRP6- expressing cancer cells. | 20446724 |
| Type | IDs |
|---|---|
| Synonymous | 2210015O11Rik, AW537813, Mesdc2, mKIAA0081, mesd, msd |
| Gene |
UniProtKB-ID:
MESD_MOUSE
UniprotKB:
Q9ERE7
UniParc:
UPI000000410C
EMBL:
AK008735,
AK031949,
AK076760,
AF311213,
BC014742,
AK076773
Ensembl:
ENSMUSG00000038503
KO:
mmu:67943
|
| Nucleutide sequences |
EMBL-CDS:
AAG33621.1,
BAB25865.1,
BAC36476.1,
AAH14742.1,
BAC27617.1,
BAC36471.1
Ensembl_TRS:
ENSMUST00000094215
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000091768
RefSeq:
NP_075892.3,
NP_001361019.1
|
| Others |
UniRef100:
UniRef100_Q9ERE7
UniRef90:
UniRef90_Q9ERE7
UniRef50:
UniRef50_Q9ERE7
UniGene:
Mm.117365
CCDS:
CCDS21415.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员