| Type | Description |
|---|---|
| Definition | serine/threonine kinase 10 |
| Date | Results | Publications |
|---|---|---|
| 2018-01-06 10:04:00 | Binding of phosphatidylinositol 4,5-biphosphate to ezrin induces a conformational change permitting the insertion of the LOK C-terminal domain to wedge apart the membrane and F-actin-binding domains of ezrin. The N-terminal LOK kinase domain can then access a site 40 residues distal from the consensus sequence that collectively direct phosphorylation of the appropriate threonine residue. | 28430576 |
| 2017-06-24 11:26:00 | The gene signature of OPA1, CTSA, NDUFA1, STK10 and PRDX1 was able to identify patients post-implant with a sensitivity of 91% and a specificity of 86% in discrimination between post-implant group and healthy controls. | 27177495 |
| 2014-05-03 10:47:00 | STK10 functions as a tumor suppressor gene, and dysfunction of STK10 activity either through polymorphism or somatic mutations may confer anti-apoptotic effects contributing to carcinogenesis. | 23842845 |
| 2013-02-23 11:24:00 | It was shown that lymphocyte-oriented and STE20 kinase were sufficient to restrict ezrin function to the apical domain. Both kinases were enriched in microvilli and locally activated there. | 23209304 |
| 2011-10-15 11:29:00 | genetic polymorphism is associated with aspirin-intolerant asthma in a Korean population | 21905501 |
| Type | IDs |
|---|---|
| Synonymous | LOK, PRO2729 |
| Gene |
UniProtKB-ID:
STK10_HUMAN
UniprotKB:
O94804
UniParc:
UPI0000136104
EMBL:
AB015718,
AL133081,
AC024561,
CH471062,
BC070077,
AK022960,
AK313350
Ensembl:
ENSG00000072786
KO:
hsa:6793
|
| Nucleutide sequences |
EMBL-CDS:
BAA35073.1,
EAW61439.1,
BAG36152.1,
CAB61400.1,
BAG51143.1,
AAH70077.1
Ensembl_TRS:
ENST00000176763
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000176763
RefSeq:
NP_005981.3,
XP_016865277.1
|
| Others |
UniRef100:
UniRef100_O94804
UniRef90:
UniRef90_O94804
UniRef50:
UniRef50_O94804
UniGene:
Hs.744005
CCDS:
CCDS34290.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员