| Type | Description |
|---|---|
| Definition | phospholipid phosphatase 3 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-11 12:32:00 | our results identify and validate the PLPP3 gene as an associated biological pathway that regulates coronary artery disease risk but is not obviously related to traditional risk factors, in particular those involving elevations in circulating cholesterol and triglycerides. | 31533471 |
| 2018-12-22 10:03:00 | Lipid phosphate phosphatase 3 regulates adipocyte sphingolipid synthesis, but not developmental adipogenesis or diet-induced obesity in mice | 29889835 |
| 2018-11-10 10:41:00 | Plpp3 ablation in mice worsened atherosclerosis development. Lipidomic analysis suggested that the hepatic Plpp3 deletion may promote atherosclerosis by increasing plasma levels of several low-abundant pro-atherogenic lipids, thus providing a molecular basis for the observed results. | 28291223 |
| 2018-07-14 10:05:00 | Lack of PLPP3 results in deteriorating cardiac function. | 28982073 |
| 2017-02-18 11:48:00 | Demonstrate essential roles of LPP3 in the maturation of endothelial cell barrier integrity and normal cardiovascular development. | 27125875 |
| Type | IDs |
|---|---|
| Synonymous | 1110003O22Rik, 2610002D05Rik, AV025606, D4Bwg0538e, D4Bwg1535e, Lpp3, PRG-2, Ppab2b, Ppap2b |
| Gene |
UniProtKB-ID:
PLPP3_MOUSE
UniprotKB:
Q99JY8
UniParc:
UPI0000022EEA
EMBL:
AK160056,
BC005558,
AK159136
Ensembl:
ENSMUSG00000028517
KO:
mmu:67916
|
| Nucleutide sequences |
EMBL-CDS:
AAH05558.1,
BAE35594.1,
BAE34848.1
Ensembl_TRS:
ENSMUST00000064139
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000065719
RefSeq:
NP_542122.1
|
| Others |
UniRef100:
UniRef100_Q99JY8
UniRef90:
UniRef90_Q99JY8
UniRef50:
UniRef50_Q99JY8
UniGene:
Mm.348326
CCDS:
CCDS18417.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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