| Type | Description |
|---|---|
| Definition | mitochondrial fission process 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-09-21 11:00:00 | the results suggest that miR-668 is induced via HIF-1 in ischemic AKI and that, upon induction, miR-668 represses MTP18 to preserve mitochondrial dynamics for renal tubular cell survival and kidney protection. | 30325740 |
| 2018-07-14 10:54:00 | Knockdown of Mtfp1 can minimize doxorubicin cardiotoxicity by inhibiting Dnm1l-mediated mitochondrial fission. | 28643438 |
| 2017-10-14 13:10:00 | Data provide direct evidence for cell survival upon mTOR inhibition through mitochondrial hyperfusion employing MTFP1 as a critical effector of mTORC1 to govern cell fate decisions. | 28918902 |
| Type | IDs |
|---|---|
| Synonymous | 1700020C11Rik, 2610507A21Rik, AV005788, Mtp18 |
| Gene |
UniProtKB-ID:
MTFP1_MOUSE
UniprotKB:
Q9CRB8
UniParc:
UPI0000029AD7
EMBL:
BC058737,
AK010971,
AK012058,
AK006148,
AK078381
Ensembl:
ENSMUSG00000004748
KO:
mmu:67900
|
| Nucleutide sequences |
EMBL-CDS:
BAB24432.1,
AAH58737.1,
BAB27999.1,
BAB27300.1,
BAC37244.1
Ensembl_TRS:
ENSMUST00000004868
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000004868
RefSeq:
NP_080719.2
|
| Others |
UniRef100:
UniRef100_Q9CRB8
UniRef90:
UniRef90_Q9CRB8
UniRef50:
UniRef50_Q9CRB8
UniGene:
Mm.41719
CCDS:
CCDS24376.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 30926747 |
A Role for Sensory end Organ-Derived Signals in Regulating Muscle Spindle Proprioceptor Phenotype. J Neurosci Dawei Wu , Ira Schieren , Yingzhi Qian , Chaolin Zhang , Thomas M Jessell , Joriene C de Nooij |
2019-05-29 | - |
| 30325740 |
MicroRNA-668 represses MTP18 to preserve mitochondrial dynamics in ischemic acute kidney injury. J Clin Invest Qingqing Wei , Haipeng Sun , Shuwei Song , Yong Liu , Pengyuan Liu , Man Jiang Livingston , Jianwen Wang , Mingyu Liang , Qing-Sheng Mi , Yuqing Huo , Norris Stanley Nahman , Changlin Mei , Zheng Dong |
2018-12-03 | - |
| 28643438 |
J. Cell. Mol. Med. Lynn H H Aung , Ruibei Li , Bellur S Prabhakar , Peifeng Li |
2017-12-01 | - |
| 28918902 |
mTOR Controls Mitochondrial Dynamics and Cell Survival via MTFP1. Mol. Cell Masahiro Morita , Julien Prudent , Kaustuv Basu , Vanessa Goyon , Sakie Katsumura , Laura Hulea , Dana Pearl , Nadeem Siddiqui , Stefan Strack , Shawn McGuirk , Julie St-Pierre , Ola Larsson , Ivan Topisirovic , Hojatollah Vali , Heidi M McBride , John J Bergeron , Nahum Sonenberg |
2017-09-21 | - |
| 26465331 |
PLoS One Julianne H Grose , Kelsey Langston , Xiaohui Wang , Shayne Squires , Soumyajit Banerjee Mustafi , Whitney Hayes , Jonathan Neubert , Susan K Fischer , Matthew Fasano , Gina Moore Saunders , Qiang Dai , Elisabeth Christians , E Douglas Lewandowski , Peipei Ping , Ivor J Benjamin |
2015-01-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 21677750 |
A conditional knockout resource for the genome-wide study of mouse gene function. Nature William C Skarnes , Barry Rosen , Anthony P West , Manousos Koutsourakis , Wendy Bushell , Vivek Iyer , Alejandro O Mujica , Mark Thomas , Jennifer Harrow , Tony Cox , David Jackson , Jessica Severin , Patrick Biggs , Jun Fu , Michael Nefedov , Pieter J de Jong , A Francis Stewart , Allan Bradley |
2011-06-15 | - |
| 21267068 |
A high-resolution anatomical atlas of the transcriptome in the mouse embryo. PLoS Biol. Graciana Diez-Roux , Sandro Banfi , Marc Sultan , Lars Geffers , Santosh Anand , David Rozado , Alon Magen , Elena Canidio , Massimiliano Pagani , Ivana Peluso , Nathalie Lin-Marq , Muriel Koch , Marchesa Bilio , Immacolata Cantiello , Roberta Verde , Cristian De Masi , Salvatore A Bianchi , Juliette Cicchini , Elodie Perroud , Shprese Mehmeti , Emilie Dagand , Sabine Schrinner , Asja Nürnberger , Katja Schmidt , Katja Metz , Christina Zwingmann , Norbert Brieske , Cindy Springer , Ana Martinez Hernandez , Sarah Herzog , Frauke Grabbe , Cornelia Sieverding , Barbara Fischer , Kathrin Schrader , Maren Brockmeyer , Sarah Dettmer , Christin Helbig , Violaine Alunni , Marie-Annick Battaini , Carole Mura , Charlotte N Henrichsen , Raquel Garcia-Lopez , Diego Echevarria , Eduardo Puelles , Elena Garcia-Calero , Stefan Kruse , Markus Uhr , Christine Kauck , Guangjie Feng , Nestor Milyaev , Chuang Kee Ong , Lalit Kumar , MeiSze Lam , Colin A Semple , Attila Gyenesei , Stefan Mundlos , Uwe Radelof , Hans Lehrach , Paolo Sarmientos , Alexandre Reymond , Duncan R Davidson , Pascal Dollé , Stylianos E Antonarakis , Marie-Laure Yaspo , Salvador Martinez , Richard A Baldock , Gregor Eichele , Andrea Ballabio |
2011-01-18 | - |
| 18614015 |
A mitochondrial protein compendium elucidates complex I disease biology. Cell David J Pagliarini , Sarah E Calvo , Betty Chang , Sunil A Sheth , Scott B Vafai , Shao-En Ong , Geoffrey A Walford , Canny Sugiana , Avihu Boneh , William K Chen , David E Hill , Marc Vidal , James G Evans , David R Thorburn , Steven A Carr , Vamsi K Mootha |
2008-07-11 |
Acacb,
Hscb,
Gadd45gip1,
Lars2,
Acad11,
Chchd10,
Nt5dc3,
Slc25a41,
Nt5m,
Cyp27a1,
Acly,
Ndufb11,
Gldc,
Rexo2,
Rars,
Aldh6a1,
Slc25a47,
Rdh14,
Ppif,
Ldhal6b,
Me2,
Glyat,
Slc25a45,
Acaca,
Nt5c3,
Mrpl10,
Mrpl41,
Mrpl30,
Aldh1l1,
Mthfs,
Shmt2,
Atic,
Mthfd1,
Mat2b,
Fam210a,
Gpt2,
Lyrm2,
Rdh13,
Mtrf1l,
Atad3a,
Rars2,
Sccpdh,
Me3,
Maob,
Dut,
Cyp11b1,
Fdps,
Akr7a5,
Msra,
Krt5,
Cox6b1,
Qdpr,
Acat1,
Acat2,
Aldh7a1,
Pcca,
Etfb,
Etfa,
Nudt19,
Acadl,
Acadm,
Acadvl,
Acaa1a,
Acads,
Aco1,
Aco2,
Prosc,
Afg3l1,
Adsl,
Agxt,
Ak2,
Ak4,
Akap1,
Alas1,
Alas2,
Abcd1,
Aldh2,
Aldh3a2,
Gfer,
Acsm1,
Slc25a4,
Slc25a5,
Prdx3,
Prdx6,
Mrps2,
Arg2,
Rhoa,
Atp5a1,
Atp5b,
Atp5c1,
Atp5f1,
Atp5g1,
Atp5j,
Atp5k,
Atpif1,
Auh,
Akr1b7,
Bad,
Bak1
|
| 18554416 |
Identification of transcripts with enriched expression in the developing and adult pancreas. Genome Biol. Brad G Hoffman , Bogard Zavaglia , Joy Witzsche , Teresa Ruiz de Algara , Mike Beach , Pamela A Hoodless , Steven J M Jones , Marco A Marra , Cheryl D Helgason |
2008-01-01 |
Fam174b,
Ugt2b34,
Emilin1,
Akap9,
Hepacam2,
Cyp4v3,
Lars2,
Gck,
Acly,
Ces1d,
Mycbpap,
Fam110c,
Card10,
Arap3,
Fam111a,
Ssr1,
Ankrd1,
Ltbp4,
Cald1,
Ctrl,
Cpa1,
Clps,
Vimp,
Cela1,
Fgb,
Rap1gap,
Acadl,
Ace,
Acp5,
Chrna1,
Tle6,
Actc1,
Actn2,
Acta2,
Adamts1,
Adcy7,
Plin2,
Afp,
Alcam,
Ambp,
Mat1a,
Amy1,
Anxa3,
Anxa4,
Ap1g2,
Aplp1,
Apoa1,
Apoa2,
Aqp1,
Arc,
Arg1,
Arx,
Ass1,
Neurod4,
Neurog3,
Atp2a2,
Bcap29,
Bex2,
Bgn,
Klf5,
Btg2,
Btk,
Serping1,
Calca,
Calm1,
Calm2,
Casp3,
Serpina6,
Cck,
Cckar,
Cd2ap,
Cd34,
Cd44,
Cdk11b,
Cdh1,
Cdkn1a,
Cdkn1c,
Cel,
Cfh,
Chga,
Chgb,
Cited1,
Cldn3,
Clu,
Cnih1,
Plk3,
Col14a1,
Col15a1,
Col3a1,
Col5a2,
Col6a1,
Col9a2,
Col1a1,
Col1a2,
Coq7,
Cox6a2,
Crabp2,
Cryba2,
Dnajc5
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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目前还没有研究热点人员