| Type | Description |
|---|---|
| Definition | transmembrane protein 33 |
| Date | Results | Publications |
|---|---|---|
| 2019-06-15 10:55:00 | Study shows that TMEM33 interacts with the ion channel polycystin-2 at the endoplasmic reticulum (ER) membrane, enhancing its opening over the whole physiological calcium range in ER liposomes fused to planar bilayers. Results identify a key role for TMEM33 in the regulation of intracellular calcium homeostasis of renal proximal convoluted tubule cells and establish a causal link between TMEM33 and acute kidney injury. | 31048699 |
| Type | IDs |
|---|---|
| Synonymous | 1110006G02Rik, 1600019D15Rik, 2410089A21Rik, 2700052H22Rik, 5430406L04Rik, AA388285, AI314185, AI426615, db83 |
| Gene |
UniProtKB-ID:
TMM33_MOUSE,
Q9CZM3_MOUSE,
A0A0R4J1Z3_MOUSE
UniprotKB:
Q9CR67,
Q9CZM3,
A0A0R4J1Z3
UniParc:
UPI00000019CD,
UPI0000024524,
UPI00000E72CE
EMBL:
AK153441,
AK005493,
AK012413,
BC016570,
AK017281,
AC102896,
BC023966,
AK007750,
AK032555,
BC005562,
AK165369,
AK007607
Ensembl:
ENSMUSG00000037720
KO:
mmu:67878
|
| Nucleutide sequences |
EMBL-CDS:
BAB25131.1,
AAH16570.1,
BAE38149.1,
BAE31997.1,
BAB24078.1,
BAB25233.1,
AAH23966.1,
BAB30671.1,
AAH05562.1,
BAC27922.1,
BAB28224.1
Ensembl_TRS:
ENSMUST00000037918,
ENSMUST00000161369,
ENSMUST00000162543,
ENSMUST00000160352
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000042852,
ENSMUSP00000124390,
ENSMUSP00000124765,
ENSMUSP00000124766
RefSeq:
NP_083251.2,
NP_001272381.1,
NP_084384.1
|
| Others |
UniRef100:
UniRef100_A0A0R4J1Z3,
UniRef100_Q9CR67,
UniRef100_Q9CZM3
UniRef90:
UniRef90_Q9Z142,
UniRef90_Q9CZM3
UniRef50:
UniRef50_Q9Z142,
UniRef50_Q9CZM3
UniGene:
Mm.23217
CCDS:
CCDS19317.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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