| Type | Description |
|---|---|
| Definition | reprimo, TP53 dependent G2 arrest mediator candidate |
| Date | Results | Publications |
|---|---|---|
| 2012-09-22 10:34:00 | RPRM is transiently up-regulated at a posttranscriptional level in times of cellular stress to restrict cell survival, proliferation, and tumor formation | 22562171 |
| 2010-01-21 00:00:00 | Induction by DNA damage and hypoxia suggest IGFBP-3 plays a role in the physiologic protection against aberrant cell growth. | 15769996 |
| 2010-01-21 00:00:00 | Oral administration of green tea or topical caffeine immediately after discontinuation of UVB treatment enhanced the rate and extent of disappearance of the mutant p53-positive patches on skin of hairless mice. | 15817611 |
| 2010-01-21 00:00:00 | p53(R273H) binds directly to the relaxin promoter, further confirming a role for H2 relaxin signaling in p53(R273H)-mediated androgen-independent prostate cancer | 16434975 |
| 2010-01-21 00:00:00 | tp53 activation occurs at a posttranslational level via chloroquine-dependent phosphorylation of the checkpoint protein {ATM)leading to ATM-dependent phosphorylation of tp53 kinase, and mediating resistance to mammary carcinogenesis. | 18089834 |
| Type | IDs |
|---|---|
| Synonymous | 2410012A13Rik, Reprimo |
| Gene |
UniProtKB-ID:
RPRM_MOUSE
UniprotKB:
Q9JJ72
UniParc:
UPI0000022A75
EMBL:
AL844850,
AB043586,
AK014769,
BC030065,
AK010465
Ensembl:
ENSMUSG00000075334
KO:
mmu:67874
|
| Nucleutide sequences |
EMBL-CDS:
BAB29541.1,
BAB01514.1,
AAH30065.1,
BAB26960.1
Ensembl_TRS:
ENSMUST00000100089
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000097667
RefSeq:
NP_075885.1
|
| Others |
UniRef100:
UniRef100_Q9JJ72
UniRef90:
UniRef90_Q9NS64
UniRef50:
UniRef50_Q9NS64
UniGene:
Mm.27086
CCDS:
CCDS16040.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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