| Type | Description |
|---|---|
| Definition | polymerase (DNA-directed), delta interacting protein 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-08-01 14:38:00 | Preservation of the differentiated phenotype in Poldip2+/- mice inhibits neointima formation after injury. Poldip2 deficiency induces a highly differentiated phenotype in VSMCs through a mechanism that involves regulation of metabolism and proteostasis. | 31656131 |
| 2020-05-16 10:20:00 | These data suggest Poldip2 mediates LPS-induced blood-brain barrier disruption by regulating NF-kappaBeta subunit p65 activation and Cox-2 and prostaglandin E2 induction. | 31779628 |
| 2020-02-22 11:53:00 | hepatic dysregulation of Poldip2 may contribute to diabetic dyslipidemia and hyperglycemia | 31351995 |
| 2019-11-23 10:32:00 | Heterozygous deletion of Poldip2 protects against lung edema and vascular inflammation in a model of acute respiratory distress syndrome. | 30622219 |
| 2019-04-13 12:06:00 | Polidip2 is up-regulated following cerebral ischemia and mediates the breakdown of the blood-brain barrier. | 29452577 |
| Type | IDs |
|---|---|
| Synonymous | 1300003F06Rik, Pdip38 |
| Gene |
UniProtKB-ID:
PDIP2_MOUSE
UniprotKB:
Q91VA6
UniParc:
UPI000002915A
EMBL:
BC006833,
BC012879
Ensembl:
ENSMUSG00000001100
KO:
mmu:67811
|
| Nucleutide sequences |
EMBL-CDS:
AAH06833.1,
AAH12879.1
Ensembl_TRS:
ENSMUST00000001127
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000001127
RefSeq:
NP_080665.1
|
| Others |
UniRef100:
UniRef100_Q91VA6
UniRef90:
UniRef90_Q91VA6
UniRef50:
UniRef50_Q91VA6
UniGene:
Mm.197493
CCDS:
CCDS25109.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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