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6780 STAU1

6780

STAU1

staufen double-stranded RNA binding protein 1

protein-coding

Homo sapiens

基因描述

Type Description
Definition staufen double-stranded RNA binding protein 1

研究结论

Date Results Publications
2021-02-20 13:28:00 PABPC1-induced stabilization of BDNF-AS inhibits malignant progression of glioblastoma cells through STAU1-mediated decay. 32015336
2021-01-23 13:02:00 3'READS + RIP defines differential Staufen1 binding to alternative 3'UTR isoforms and reveals structures and sequence motifs influencing binding and polysome association. 32796083
2021-01-02 12:50:00 Staufen1 is Essential for Cell-Cycle Transitions and Via the Control of E2F1 Expression. 32335035
2020-06-20 10:23:00 we present the first solution structure models for full-length hStaufen1(55), showing that its domains are arranged as beads-on-a-string connected by flexible linkers. In analogy with other nucleic acid-binding proteins, this could underpin Stau1 functional plasticity. 31852734
2020-03-21 11:22:00 Mutants disrupting minor groove recognition of ARF1 SBS affect in vitro binding and reduce STAU1-mediated mRNA decay (SMD) in vivo. Our data thus reveal how STAU1 recognizes minor groove features in dsRNA relevant for target selection 31875226

名称对应

Type IDs
Synonymous PPP1R150, STAU
Gene
UniProtKB-ID: STAU1_HUMAN, Q6PJX3_HUMAN, B3KRE0_HUMAN, Q59F99_HUMAN
UniprotKB: O95793, Q6PJX3, B3KRE0, Q59F99
UniParc: UPI0000072A0D, UPI000013CB53, UPI00004F6D4B, UPI00001BD9BB, UPI00004A3A24, UPI000178DFC5
EMBL: BC050432, AK091405, AB209561, AF061940, BC095397, AF061941, CH471077, AY529074, AK292859, AF061938, AL136601, AL133174, AF061939, AJ132258, AY546099, BC010169
Ensembl: ENSG00000124214
KO: hsa:6780
Nucleutide sequences
EMBL-CDS: AAD17533.1, BAF85548.1, CAB66536.1, EAW75673.1, AAH50432.1, EAW75672.1, CAB40082.1, AAD17530.1, AAS76637.1, AAD17531.1, EAW75674.1, AAD17532.1, EAW75671.1, AAS76636.1, AAH95397.1, EAW75669.1, AAH10169.1, BAG52352.1, BAD92798.1
Ensembl_TRS: ENST00000371828, ENST00000347458, ENST00000360426, ENST00000371856, ENST00000371802, ENST00000340954
Protein sequencees
Ensembl_PRO: ENSP00000345425, ENSP00000353604, ENSP00000360867, ENSP00000360922, ENSP00000360893, ENSP00000323443
RefSeq: NP_004593.2, NP_001309860.1, XP_005260584.1, NP_059348.2, XP_006723928.1, XP_011527317.1, NP_001309858.1, NP_001309856.1, NP_001309857.1, NP_001309861.1, NP_001309862.1, NP_001309859.1, NP_059346.2, NP_059347.2, NP_001032405.1, NP_001306063.1, XP_016883517.1, NP_001306064.1, XP_024307741.1
Others
UniRef100: UniRef100_Q6PJX3, UniRef100_O95793
UniRef90: UniRef90_O95793, UniRef90_Q6PJX3
UniRef50: UniRef50_O95793, UniRef50_Q6PJX3
UniGene: Hs.596704
CCDS: CCDS33481.1, CCDS13415.1, CCDS13414.1

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