| Type | Description |
|---|---|
| Definition | NADH dehydrogenase subunit 1 |
| Date | Results | Publications |
|---|---|---|
| 2017-08-19 12:43:00 | It was concluded that the loss of ND1 stalls complex I assembly during the early stages of its biogenesis, which not only results in the loss of mature complex I but also disrupts the stability of complex IV and the respiratory supercomplex to cause mitochondrial dysfunction.- | 26929434 |
| 2016-07-30 11:10:00 | Compound mtDNA mutations of m.3635G > A and m.14502T > C presented with low penetration, and the patients with these compound mutations exhibited mild visual impairment. | 24417559 |
| 2015-07-25 11:30:00 | This mutation expands the spectrum of deleterious changes in mitochondrial DNA-encoded complex I polypeptides associated with sporadic Leber hereditary optic neuropathy patients. | 24800637 |
| 2014-11-08 11:15:00 | Mutations in ND1 is associated with peripheral neuropathy of diabetes. | 24456990 |
| 2012-10-06 11:13:00 | ND1 T3866C mutation leads to LHON. This mutation may be insufficient to produce a clinical phenotype. Other modifier factors may contribute to the phenotypic manifestation of the T3866C mutation. | 22577081 |
| Type | IDs |
|---|---|
| Gene |
UniProtKB-ID:
A0A059UBJ6_HOMNE,
B4F448_HOMNE
UniprotKB:
A0A059UBJ6,
B4F448
UniParc:
UPI00045ECA6D,
UPI00017BBF1C
EMBL:
MK388903,
KJ533544,
AM948965,
MG025537,
KX198087,
KX198083,
MG025540,
MG025539,
KX198085,
KX198088,
FM865407,
FM865408,
KX198086,
FM865410,
MG025538,
KJ533545,
FM865409,
KU131206,
KX198084,
MG025536
|
| Nucleutide sequences |
EMBL-CDS:
AUD37523.1,
QIT06494.1,
AUD37484.1,
ANC95176.1,
AUD37497.1,
AMQ34011.1,
AUD37471.1,
ANC95189.1,
ANC95202.1,
AHZ61446.1,
ANC95163.1,
AUD37510.1,
AHZ61459.1,
ANC95137.1,
ANC95150.1,
CAR95801.1,
CAR95840.1,
CAR95827.1,
CAR95814.1,
CAQ37646.1
|
| Protein sequencees |
RefSeq:
YP_002124302.2
|
| Others |
UniRef100:
UniRef100_A0A059UBJ6
UniRef90:
UniRef90_P03886
UniRef50:
UniRef50_P03886
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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