Type | Description |
---|---|
Definition | NADH dehydrogenase subunit 5 |
Date | Results | Publications |
---|---|---|
2019-02-16 11:23:00 | In this study, we demonstrated that a missense mutation (m.12338T>C, p.1M>T) in the ND5 gene contributed to the pathogenesis of Leber's hereditary optic neuropathy (LHON) . The m.12338T>C mutation affected the first methionine (Met1) with a threonine and shortened two amino acids of ND5 | 29579248 |
2018-03-17 11:09:00 | The authors propose that somatic mutation ND5:P265H resulted in down-regulated complex I enzyme activity, elevated and up-regulation of a set of nuclear anti-apoptotic genes epigenetically in a P53 dysfunctional cellular background generating pro-cancerous phenotypes. | 28502718 |
2016-10-22 11:34:00 | Calcium signaling in a cellular model consisting of fibroblasts from patients carrying mutations in the mitochondrial ND5 gene. | 26206091 |
2014-11-08 11:15:00 | Mutations in ND5 is associated with peripheral neuropathy of diabetes. | 24456990 |
2014-03-08 12:28:00 | Mutations in ND5, expected to inhibit complex I activity, could lead to generation of oxidative stress and favor glaucomatous condition. | 23940637 |
Type | IDs |
---|---|
Gene |
UniProtKB-ID:
B4F445_HOMNE
UniprotKB:
B4F445
UniParc:
UPI00017BBF22
EMBL:
MG025538,
FM865410,
KX198086,
KJ533545,
FM865408,
KX198084,
KU131206,
FM865409,
MG025537,
AM948965,
KJ533544,
MK388903,
KX198088,
FM865407,
KX198083,
KX198087,
KX198085,
MG025539,
MG025540
|
Nucleutide sequences |
EMBL-CDS:
AHZ61456.1,
AUD37507.1,
ANC95212.1,
CAR95811.1,
AUD37494.1,
CAR95824.1,
AUD37520.1,
ANC95186.1,
ANC95147.1,
CAQ37656.1,
ANC95160.1,
CAR95837.1,
CAR95850.1,
AMQ34021.1,
ANC95173.1,
QIT06504.1,
ANC95199.1,
AHZ61469.1,
AUD37533.1
|
Protein sequencees |
RefSeq:
YP_002124312.1
|
Others |
UniRef100:
UniRef100_B4F445
UniRef90:
UniRef90_P03915
UniRef50:
UniRef50_P03915
|
{{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
---|---|---|---|---|---|---|---|---|
Refseq |
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