| Type | Description |
|---|---|
| Definition | SAM domain, SH3 domain and nuclear localization signals, 1 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 11:19:00 | We also carried out transgene rescue by adding Sly1/2 transgenes to mice with NPYq deletions. We demonstrated that SLY1/2 expression in mutant mice decreased proportionally to deletion size, with ~12% of SLY1/2 retained in shSLY sh367 testes. | 30759861 |
| 2015-04-11 10:42:00 | This is the first study to identify deletion of a key gene in the C57BL/KaLwRij mice that also displays reduced gene expression in patients with MM and is therefore likely to play an integral role in MM disease development. | 25117979 |
| 2015-03-28 12:32:00 | SLy2 controls the antibody response to pneumococcal vaccine through an IL-5Ralpha-dependent mechanism in B-1 cells. | 25330943 |
| 2011-07-02 10:50:00 | the immunoinhibitory roles of SLy2 in vivo and suggest that the physiological up-regulation of SLy2 observed upon B cell activation functions to counteract excessive B cell spreading. | 21296879 |
| 2010-05-31 11:35:00 | This study suggests that Hacs1 is an immunoinhibitory adaptor that might be a useful target for immune suppression therapy. | 19923443 |
| Type | IDs |
|---|---|
| Synonymous | 4930571B16Rik, 930571B16Rik, Hacs1, SLy2 |
| Gene |
UniProtKB-ID:
SAMN1_MOUSE
UniprotKB:
P57725
UniParc:
UPI00000E9ADD
EMBL:
BC052906,
BC064778,
DQ333189,
AK053946,
AF222928
Ensembl:
ENSMUSG00000022876
KO:
mmu:67742
|
| Nucleutide sequences |
EMBL-CDS:
AAG23356.1,
AAH64778.1,
AAH52906.1,
ABC59720.1,
BAC35601.1
Ensembl_TRS:
ENSMUST00000114239
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000109877
RefSeq:
NP_075869.2
|
| Others |
UniRef100:
UniRef100_P57725
UniRef90:
UniRef90_P57725
UniRef50:
UniRef50_P57725
UniGene:
Mm.131406
CCDS:
CCDS37378.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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