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67709 Reg4

67709

Reg4

regenerating islet-derived family, member 4

protein-coding

Mus musculus

基因描述

Type Description
Definition regenerating islet-derived family, member 4

研究结论

Date Results Publications
2019-11-16 13:08:00 Cardiomyocytes situated in close proximity to the infarcted region produce large amounts of Reg3b, Reg3g, and Reg4, thereby forming a chemokine gradient that might direct interstitial migration of MHCIIhi/Ly6Clo and MHC-IIlo/Ly6Clo macrophage subsets. 29850784
2018-01-27 10:20:00 sorted Reg4(+) DCS cells promote organoid formation of single Lgr5(+) colon stem cells. DCS cells can be massively produced from Lgr5(+) colon stem cells in vitro by combined Notch inhibition and Wnt activation 27573849
2011-07-16 11:18:00 data suggest that Reg4 may protect against acinar cell necrosis in experimental pancreatitis by enhancing the expression of Bcl-2 and Bcl-xL via activation of the EGFR/Akt signalling pathway. 21193457
2010-04-12 11:38:00 Reg IV as an important modulator of gastrointestinal cell susceptibility to irradiation; hence, it is a potential target for adjunctive treatments for human colorectal cancer and other gastrointestinal malignancies. 19900450
2010-03-15 12:29:00 reg4 is amplified in the early stages of pancreatic cancer development 19834624

名称对应

Type IDs
Synonymous 2010002L15Rik, GISP, RELP
Gene
UniProtKB-ID: REG4_MOUSE
UniprotKB: Q9D8G5
UniParc: UPI0000022D14
EMBL: AK162316, AK008438, AK008049, BC019465
Ensembl: ENSMUSG00000027876
KO: mmu:67709
Nucleutide sequences
EMBL-CDS: BAB25669.1, BAE36851.1, BAB25429.1, AAH19465.1
Ensembl_TRS: ENSMUST00000029469
Protein sequencees
Ensembl_PRO: ENSMUSP00000029469
RefSeq: XP_017175186.1, NP_080604.2
Others
UniRef100: UniRef100_Q9D8G5
UniRef90: UniRef90_Q9D8G5
UniRef50: UniRef50_Q9D8G5
UniGene: Mm.46306
CCDS: CCDS17661.1

全选

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