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67680 Sdhb

67680

Sdhb

succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

protein-coding

Mus musculus

基因描述

Type Description
Definition succinate dehydrogenase complex, subunit B, iron sulfur (Ip)

研究结论

Date Results Publications
2021-03-27 14:40:00 TET-Mediated Hypermethylation Primes SDH-Deficient Cells for HIF2alpha-Driven Mesenchymal Transition. 32234487
2019-01-19 11:04:00 the present study identified a potential role for the tumor microenvironment in influencing phenotypic features of SDHB-mutated Pheochromocytomas and paragangliomas. 30159755
2016-01-30 11:57:00 Data show that lack of succinate dehydrogenase (SDH) activity commits cells to consume extracellular pyruvate. 26302408
2015-10-03 10:45:00 Using Sdhb(+/-) mice, we provide evidence that pituitary hyperplasia in SDHx-deficient cells may be the initial abnormality in the cascade of events leading to pituitary adenoma formation. 25695889
2012-09-01 11:06:00 Tumor-derived FH and SDH mutations accumulate fumarate and succinate, leading to enzymatic inhibition of multiple alpha-KG-dependent dioxygenases and consequent alterations of genome-wide histone and DNA methylation. 22677546

名称对应

Type IDs
Synonymous 0710008N11Rik
Gene
UniProtKB-ID: SDHB_MOUSE
UniprotKB: Q9CQA3
UniParc: UPI000002115D
EMBL: BC013509, AK009660, BC051934, AK003052, AK153045, AK169252, AK003533
Ensembl: ENSMUSG00000009863
KO: mmu:67680
Nucleutide sequences
EMBL-CDS: AAH13509.1, AAH51934.1, BAB22842.1, BAE41016.1, BAE31674.1, BAB26422.1, BAB22534.1
Ensembl_TRS: ENSMUST00000010007
Protein sequencees
Ensembl_PRO: ENSMUSP00000010007
RefSeq: NP_075863.2, NP_001342444.1
Others
UniRef100: UniRef100_Q9CQA3
UniRef90: UniRef90_Q9CQA3
UniRef50: UniRef50_Q9CQA3
UniGene: Mm.246965
CCDS: CCDS18858.1

全选

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研究热度

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