| Type | Description |
|---|---|
| Definition | suppression of tumorigenicity 5 |
| Date | Results | Publications |
|---|---|---|
| 2020-04-25 12:43:00 | Findings provide evidence of suppression of tumorigenicity 5 (ST5) involvement in positive regulation of osteoclastogenesis via src Kinases (Src)/Syk Kinase (Syk)/calcium signaling. | 31707778 |
| 2018-08-04 12:23:00 | Here, we discover that intersectin-s binds DENND2B, a guanine nucleotide exchange factor for the exocytic GTPase Rab13, and this interaction promotes recycling of ligand-free EGFR to the cell surface. Our study thus reveals a novel mechanism controlling the fate of internalized EGFR with important implications for cancer. | 29030480 |
| 2015-05-02 12:56:00 | DENND2B interacts with the Rab13 effector MICAL-L2 at the cell periphery, and this interaction is required for the dynamic remodeling of the cell's leading edge. | 25713415 |
| 2010-06-30 22:06:00 | Clinical trial of gene-disease association and gene-environment interaction. (HuGE Navigator) | 20379614 |
| 2010-05-10 11:43:00 | Using RNA in situ hybridisation in mouse, the authors found that St5 is expressed in the frontal cortex during embryonic development. In adult mouse brain, expression of St5 was especially high in the hippocampal area and cerebellum. | 19843505 |
| Type | IDs |
|---|---|
| Synonymous | DENND2B, HTS1, p126 |
| Gene |
UniProtKB-ID:
DEN2B_HUMAN
UniprotKB:
P78524
UniParc:
UPI00001AECB8,
UPI000016B159,
UPI000006CFFA
EMBL:
CH471064,
AK127763,
AC091053,
U15131,
AC026894,
U15779,
S45936,
BC036655,
AK312758,
AJ400879,
U15780
Ensembl:
ENSG00000166444
KO:
hsa:6764
|
| Nucleutide sequences |
EMBL-CDS:
AAC50925.1,
AAB23647.1,
EAW68618.1,
AAB97097.1,
AAC50926.1,
CAC35387.1,
BAG54568.1,
AAH36655.1,
BAG35624.1
Ensembl_TRS:
ENST00000534127,
ENST00000313726,
ENST00000530991,
ENST00000530438,
ENST00000526757
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000435097,
ENSP00000319678,
ENSP00000433528,
ENSP00000436802,
ENSP00000432887
RefSeq:
NP_001363425.1,
NP_001363431.1,
NP_001363429.1,
XP_011518626.2,
NP_001363435.1,
XP_005253134.1,
NP_001363424.1,
XP_011518623.1,
NP_001363433.1,
NP_001363430.1,
NP_001363427.1,
NP_998783.1,
NP_005409.3,
NP_001363432.1,
XP_011518622.1,
NP_001363434.1,
NP_631896.1,
XP_011518611.1,
NP_001363426.1,
NP_001363428.1,
XP_011518624.1,
XP_011518631.1
|
| Others |
UniRef100:
UniRef100_P78524
UniRef90:
UniRef90_P78524
UniRef50:
UniRef50_P78524
UniGene:
Hs.117715
CCDS:
CCDS7792.1,
CCDS7791.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员