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67634 Ftmt

67634

Ftmt

ferritin mitochondrial

protein-coding

Mus musculus

基因描述

Type Description
Definition ferritin mitochondrial

研究结论

Date Results Publications
2020-08-12 15:29:00 In a model of FtMT overexpression, during dietary challenge, mice are leaner but exhibit glucose intolerance, low adiponectin levels, increased reactive oxygen species damage, and elevated GDF15 and FGF21 levels, indicating metabolically dysfunctional fat. Despite harboring highly dysfunctional fat, mice display massive beta-cell hyperplasia, reflecting a beneficial mitochondria-induced fat-to-pancreas interorgan signa... 31882562
2018-06-30 10:59:00 Lack of mitochondrial ferritin aggravated neurological deficits via enhancing oxidative stress in a traumatic brain injury murine model. 28963372
2017-10-21 10:21:00 Age-related increase is found in FtMt and hypoxia-inducible factor-1a (HIF-1a) in murine retinal pigment epithelium (RPE).HIF-1alpha stabilization reduced the protein level of the mature, functional form of mitochondrial ferritin. 27599360
2010-01-21 00:00:00 ferritin H not only responds to changes in tissue iron (its classic role), but can actively regulate overall tissue iron balance 16448386
2010-01-21 00:00:00 Our results provide evidence that the iron storage function of ferritin plays a major role in preventing iron-mediated cell and tissue damage. 19492434

名称对应

Type IDs
Synonymous 4930447C24Rik, FerH, Fth3, MtF
Gene
UniProtKB-ID: FTMT_MOUSE
UniprotKB: Q9D5H4
UniParc: UPI0000505496
EMBL: AK015346, AK015400, BC115515, BC115514, AK133009
Ensembl: ENSMUSG00000024510
KO: mmu:67634
Nucleutide sequences
EMBL-CDS: AAI15515.1, BAE21468.1, AAI15516.1, BAB29831.1, BAB29806.1
Ensembl_TRS: ENSMUST00000025388
Protein sequencees
Ensembl_PRO: ENSMUSP00000025388
RefSeq: NP_080562.2
Others
UniRef100: UniRef100_Q9D5H4
UniRef90: UniRef90_Q9D5H4
UniRef50: UniRef50_Q8N4E7
UniGene: Mm.179144
CCDS: CCDS29246.1

全选

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研究热度

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