| Type | Description |
|---|---|
| Definition | AKT1 substrate 1 (proline-rich) |
| Date | Results | Publications |
|---|---|---|
| 2020-08-13 15:34:00 | This study, for the first time, links PF4's anti-RNV function to an intracellular signaling molecule PRAS40 and its phosphorylation. | 31740404 |
| 2017-06-24 11:44:00 | Overexpression of PRAS40(T246A) in the Proliferative Compartment Suppresses mTORC1 Signaling, Keratinocyte Migration, and Skin Tumor Development | 27349859 |
| 2017-05-20 11:52:00 | PRAS40 inhibits mTORC1 hyperactivation and plays a key role in protecting cells against neurotoxic prion peptide-induced apoptosis. Thus, PRAS40 is a potential therapeutic target for prion disease. | 28294542 |
| 2014-09-27 12:46:00 | PRAS40 appears to reduce brain injury following ischemic stroke by converting cell signaling from Akt to mTOR | 24583056 |
| 2014-07-26 12:40:00 | PRAS40 treatment improves hepatic insulin sensitivity and reduces systemic hyperglycaemia in obese mice. | 24408966 |
| Type | IDs |
|---|---|
| Synonymous | 1110012J22Rik, AI227026, Lobe, Lobel, PRAS40 |
| Gene |
UniProtKB-ID:
AKTS1_MOUSE,
E9QKI5_MOUSE,
E9QKI4_MOUSE
UniprotKB:
Q9D1F4,
E9QKI5,
E9QKI4
UniParc:
UPI00015AA4D7,
UPI00015AA4DC,
UPI00000211D9
EMBL:
BC132372,
BC132374,
AK003638,
AK141771,
AC158231,
AK154110
Ensembl:
ENSMUSG00000011096
KO:
mmu:67605
|
| Nucleutide sequences |
EMBL-CDS:
BAE32383.1,
AAI32373.1,
BAE24829.1,
AAI32375.1,
BAB22905.1
Ensembl_TRS:
ENSMUST00000054343,
ENSMUST00000107880,
ENSMUST00000107882,
ENSMUST00000107885
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000103512,
ENSMUSP00000049764,
ENSMUSP00000103514,
ENSMUSP00000103517
RefSeq:
NP_001240849.1,
NP_001369410.1,
NP_001369412.1,
XP_036009275.1,
NP_001369409.1,
NP_001277624.1,
XP_006541181.1,
NP_001369411.1,
XP_006541180.1,
NP_001369413.1,
XP_030098797.1,
NP_080546.1,
NP_001277623.1
|
| Others |
UniRef100:
UniRef100_E9QKI5,
UniRef100_Q9D1F4
UniRef90:
UniRef90_Q9D1F4
UniRef50:
UniRef50_Q96B36
UniGene:
Mm.148007,
Mm.491121
CCDS:
CCDS21218.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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