| Type | Description |
|---|---|
| Definition | dual specificity phosphatase 6 |
| Date | Results | Publications |
|---|---|---|
| 2021-03-20 13:32:00 | Mice lacking DUSP6/8 have enhanced ERK1/2 activity and resistance to diet-induced obesity. | 32917360 |
| 2020-04-11 11:54:00 | demonstrate that DUSP6 phosphatase, by controlling ERK1/2 activation, regulates colonic inflammatory responses, and protects the intestinal epithelium against oncogenic stress | 30273442 |
| 2019-06-08 12:30:00 | data identify DUSP6 as an important regulator of ERK activity in the setting of muscle growth and muscular dystrophy | 30289454 |
| 2019-03-02 10:18:00 | DUSP6 is important for TNF-alpha-induced endothelial ICAM-1 expression in aorta and in vein. Genetic deletion of Dusp6 in pulmonary circulation significantly alleviated the susceptibility of mice to lung injury caused by neutrophil recruitment during experimental sepsis induced by TNF-alpha or lipopolysaccharide. | 29493888 |
| 2018-10-13 10:29:00 | 257 genes among 55,681 genes examined were up-regulated after 30-min treatment of GT1-7 cells with GnRH. These up-regulated genes included four dual-specificity MAPK phosphatases (DUSPs), DUSP1, DUSP2, DUSP5, and DUSP6. | 29899190 |
| Type | IDs |
|---|---|
| Synonymous | 1300019I03Rik, MKP-3, MKP3, PYST1 |
| Gene |
UniProtKB-ID:
DUS6_MOUSE
UniprotKB:
Q9DBB1
UniParc:
UPI00000041A8
EMBL:
BC003869,
AK088468,
AK159146,
AK159502,
AK159900,
AK005062,
AK088665,
AK009131
Ensembl:
ENSMUSG00000019960
KO:
mmu:67603
|
| Nucleutide sequences |
EMBL-CDS:
BAC40372.1,
BAE35135.1,
BAE34853.1,
BAE35465.1,
BAB26093.1,
BAB23786.1,
BAC40489.1,
AAH03869.1
Ensembl_TRS:
ENSMUST00000020118
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000020118
RefSeq:
NP_080544.1,
XP_036011858.1
|
| Others |
UniRef100:
UniRef100_Q9DBB1
UniRef90:
UniRef90_Q16828
UniRef50:
UniRef50_Q16828
UniGene:
Mm.1791
CCDS:
CCDS24147.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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