| Type | Description |
|---|---|
| Definition | bromodomain testis associated |
| Date | Results | Publications |
|---|---|---|
| 2018-11-10 12:00:00 | FBP1 modulates the sensitivity of pancreatic cancer cells to BET inhibitors by decreasing the expression of c-Myc. These findings highlight FBP1 could be used as a therapeutic niche for patient-tailored therapies | 30201002 |
| 2017-10-28 12:24:00 | The bromodomain and extraterminal domain (BET) family consists of BRDT, BRD2, BRD3, and BRD4, each containing 2 bromodomains located N-terminal to extraterminal domain, which is located near C-terminus. Data suggest that 10 distinct acylations participate in binding of BET family proteins to histone 4 (oligopeptide fragments used here); C-terminal bromodomains do not cooperatively bind multiple acylation sites. | 28945351 |
| 2017-09-02 13:34:00 | The affected patient carries a homozygous bromodomain, testis-specific protein (BRDT) mutation, while the patient's father, mother and elder brother all carry heterozygous BRDT mutations. | 28199965 |
| 2015-09-26 20:41:00 | considered potential associations of 14 single nucleotide polymorphisms (SNPs) in RNF8 and BRDT genes in Chinese patients with non-obstructive azoospermia | 25374327 |
| 2015-02-14 10:10:00 | assessment of rs3088232 frequency in large group of non-obstructive azoospermia men and fertile controls demonstrated no significant difference between them; conclude that testicular impairments observed were not a consequence of BRDT gene mutation | 24865796 |
| Type | IDs |
|---|---|
| Synonymous | BRD6, CT9, SPGF21 |
| Gene |
UniProtKB-ID:
BRDT_HUMAN
UniprotKB:
Q58F21
UniParc:
UPI00019863B1,
UPI000292A27D,
UPI000013D0E1,
UPI000022B087,
UPI000206505C
EMBL:
CH471097,
AK316442,
AK302758,
BC047900,
AC114486,
BC005281,
AF019085,
AK303008,
AY338951,
BC062700,
BC017582
Ensembl:
ENSG00000137948
KO:
hsa:676
|
| Nucleutide sequences |
EMBL-CDS:
BAH13797.1,
BAH13876.1,
EAW73108.1,
AAB87862.1,
AAH17582.1,
AAH62700.1,
EAW73107.1,
AAH05281.1,
EAW73111.1,
AAQ16198.1,
AAH47900.1,
EAW73110.1,
BAH14813.1,
EAW73106.1
Ensembl_TRS:
ENST00000399546,
ENST00000370389,
ENST00000402388,
ENST00000362005,
ENST00000394530
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000384051,
ENSP00000354568,
ENSP00000378038,
ENSP00000387822,
ENSP00000359416
RefSeq:
XP_011540338.1,
XP_011540335.1,
XP_006710917.1,
XP_006710916.1,
NP_001229736.2,
NP_001717.3,
XP_011540336.1,
NP_001229737.2,
XP_006710919.1,
NP_001229739.2,
NP_997072.2,
XP_006710920.1,
XP_011540337.1,
XP_006710918.1,
NP_001229734.2,
NP_001229735.2,
XP_011540334.1
|
| Others |
UniRef100:
UniRef100_Q58F21
UniRef90:
UniRef90_Q58F21
UniRef50:
UniRef50_Q58F21
UniGene:
Hs.482520
CCDS:
CCDS72820.1,
CCDS55616.1,
CCDS735.1,
CCDS55615.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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