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6757 SSX2

6757

SSX2

SSX family member 2

protein-coding

Homo sapiens

基因描述

Type Description
Definition SSX family member 2

研究结论

Date Results Publications
2020-08-29 12:46:00 A functional genetic screen identifies the Mediator complex as essential for SSX2-induced senescence. 31695025
2019-01-19 11:33:00 co-expression of and interplay between Rab3IP and SSX2 during gastric cancer progression 30005870
2018-02-03 11:45:00 We conclude from these findings that SSX2 expression in prostate cancer is not a driver of the epithelial to mesenchymal transition (EMT), but is involved in processes associated with EMT including loss of focal adhesion that may be related to tumor cell dissemination 27276714
2017-09-02 11:55:00 Meta-analysis of human synovial sarcoma patient series identified two tumor-gentoype-phenotype correlations that were not modeled by the mice, namely a scarcity of male hosts and biphasic histologic features among SS18-SSX2 tumors. Re-analysis of human SS18-SSX1 and SS18-SSX2 tumor transcriptomes demonstrated very few consistent differences, but highlighted increased native SSX2 expression in SS18-SSX1 tumors. 26947017
2015-09-26 13:13:00 results reveal two important phenotypes of ectopic SSX2 expression that may drive/support tumorigenesis: First, immediate induction of genomic instability, and second, long-term support of tumor cell growth. 25363656

名称对应

Type IDs
Synonymous CT5.2, CT5.2A, HD21, HOM-MEL-40, SSX
Gene
UniProtKB-ID: SSX2_HUMAN, R9QTR3_HUMAN
UniprotKB: Q16385, R9QTR3
UniParc: UPI0000044419, UPI000006D209, UPI000342562C
EMBL: BC007343, JX014236, BC069313, BC002818, BC103863, BC016957, AL445236, BC071827, S79894, X79200, AL450023, S79332, X86175
Ensembl: ENSG00000268447, ENSG00000241476
KO: hsa:6757, hsa:727837
Nucleutide sequences
EMBL-CDS: AAH71827.1, AAB35674.1, AAH16957.1, CAA60111.1, AAH07343.1, CAI41624.1, AAH69313.1, CAI41623.1, AAI03864.1, AAB35379.1, AAH02818.1, AGC59876.1
Ensembl_TRS: ENST00000616191, ENST00000612490, ENST00000336777, ENST00000596480, ENST00000337502
Protein sequencees
Ensembl_PRO: ENSP00000477922, ENSP00000478714, ENSP00000470740, ENSP00000338561, ENSP00000338796
RefSeq: NP_001265626.1, NP_783629.1, NP_003138.3
Others
UniRef100: UniRef100_Q16385, UniRef100_R9QTR3
UniRef90: UniRef90_Q16385, UniRef90_A0A2I3SMG8
UniRef50: UniRef50_Q16385
UniGene: Hs.289105, Hs.661107
CCDS: CCDS14345.2, CCDS65267.1, CCDS48129.1, CCDS14344.2

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