| Type | Description |
|---|---|
| Definition | SSX family member 1 |
| Date | Results | Publications |
|---|---|---|
| 2018-12-22 10:18:00 | SS18-SSX1 deregulates developmental programs to drive transformation by hijacking a transcriptional repressive complex to aberrantly activate gene expression | 29502955 |
| 2018-10-13 10:28:00 | Synovial sarcoma (SS) is considered as high-grade tumors with a poor prognosis. Novel therapies targeted at fusion oncogene, SS18-SSX-derived peptide vaccine, epidermal growth factor receptor, and vascular endothelial growth factor are the future hope in SS. | 29893303 |
| 2018-02-17 11:38:00 | Data indicate that the oncogene SS18-SSX1 promotes tumorigenesis by increasing the expression of SHC SH2-domain binding protein 1 (SHCBP1), which normally acts as a tumor promoting factor. | 27572315 |
| 2017-09-02 12:41:00 | In patients with Colon cancer, the expression of SSX1 gene was associated with a poor prognosis. | 28631709 |
| 2017-09-02 11:55:00 | Meta-analysis of human synovial sarcoma patient series identified two tumor-gentoype-phenotype correlations that were not modeled by the mice, namely a scarcity of male hosts and biphasic histologic features among SS18-SSX2 tumors. Re-analysis of human SS18-SSX1 and SS18-SSX2 tumor transcriptomes demonstrated very few consistent differences, but highlighted increased native SSX2 expression in SS18-SSX1 tumors. | 26947017 |
| Type | IDs |
|---|---|
| Synonymous | CT5.1, SSRC |
| Gene |
UniProtKB-ID:
SSX1_HUMAN
UniprotKB:
Q16384
UniParc:
UPI0000136052
EMBL:
BC128611,
BC133693,
BC001003,
X86174,
BC150487,
AL683817,
BC125151,
S79325
Ensembl:
ENSG00000126752
KO:
hsa:6756
|
| Nucleutide sequences |
EMBL-CDS:
AAI50488.1,
CAI41141.1,
AAI28612.1,
CAA60110.1,
AAB35378.1,
AAI25152.1,
AAI33694.1,
AAH01003.1
Ensembl_TRS:
ENST00000376919
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000366118
RefSeq:
NP_005626.1,
NP_001265620.1
|
| Others |
UniRef100:
UniRef100_Q16384
UniRef90:
UniRef90_Q16384
UniRef50:
UniRef50_Q16384
UniGene:
Hs.434142
CCDS:
CCDS14290.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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