| Type | Description |
|---|---|
| Definition | somatostatin receptor 5 |
| Date | Results | Publications |
|---|---|---|
| 2019-12-14 12:38:00 | Study of transgenic HP5 mice overexpressing human in pituitary corticotrophs shows that miR-449c suppresses both CRHR1 expression and function and concludes that corticotroph duanyu1942R5 attenuates hypothalamic-pituitary-adrenal axis responses via CRHR1 downregulation, suggesting a role for duanyu1942R5 in the pathogenesis of secondary adrenal insufficiency. | 30282821 |
| 2018-02-10 11:47:00 | Somatostatin receptor 5 variant (sst5TMD4) was expressed in a subset of breast cancers, where it correlated with angiogenic markers, lymphatic metastasis, and reduced disease-free survival. | 27507050 |
| 2017-11-26 00:38:00 | sst5TMD4 is overexpressed in PCa, especially in those patients with a worse prognosis, and plays an important pathophysiologic role in PCa, which suggesting its potential as a biomarker and/or therapeutic target | 28705809 |
| 2017-11-11 13:21:00 | In cotransfected HEK-293 cells, and CB1R existed in a constitutive heteromeric complex under basal condition, which was disrupted upon agonist treatments. Furthermore, concurrent receptor activation led to preferential formation of duanyu1942R5 homodimer and dissociation of CB1R homodimer. | 27984180 |
| 2017-02-18 12:02:00 | Combination treatment increased both and mRNA and protein levels in DU-145 cells. The data suggest that this combination therapy may be a good candidate for patients with advanced metastatic Prostate cancer (PCa) do not respond to androgen deprivation. | 26531719 |
| Type | IDs |
|---|---|
| Synonymous | SS-5-R |
| Gene |
UniProtKB-ID:
SSR5_HUMAN
UniprotKB:
P35346
UniParc:
UPI00000015DC
EMBL:
AE006466,
CH471112,
AY081193,
AL031713,
D16827,
L14865
Ensembl:
ENSG00000162009
KO:
hsa:6755
|
| Nucleutide sequences |
EMBL-CDS:
AAL88744.1,
AAK61266.1,
AAA20828.1,
EAW85687.1,
BAA04107.1
Ensembl_TRS:
ENST00000293897
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000293897
RefSeq:
NP_001166031.1,
NP_001044.1
|
| Others |
UniRef100:
UniRef100_P35346
UniRef90:
UniRef90_P35346
UniRef50:
UniRef50_P35346
UniGene:
Hs.449840
CCDS:
CCDS10429.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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