| Type | Description |
|---|---|
| Definition | solute carrier family 39 (metal ion transporter), member 8 |
| Date | Results | Publications |
|---|---|---|
| 2020-06-06 12:01:00 | The knockdown of Zip8 impaired activity of the Mn-dependent SOD2. | 31086870 |
| 2019-11-02 11:45:00 | Study in Slc39a8(neo/neo) knockdown mice conclude that deficient ZIP8-mediated divalent cation transport affects zinc-finger (e.g. GATA proteins) and other transcription factors interacting with GATA proteins (e.g. TAL1), predominantly in yolk sac. These data strongly support the phenotype of dysmorphogenesis and anemia seen in Slc39a8(neo/neo) mice in utero. | 30013175 |
| 2019-08-17 11:07:00 | Hepatic ZIP8 knockdown leads to selenium deficit, liver pathology, oxidative stress and tumor formation. | 29927321 |
| 2019-07-20 10:10:00 | Slc39a8 is expressed in the developing heart and regulates Zn levels. Slc39a8 deletion results in hypertrabeculation and noncompaction. | 29337306 |
| 2018-01-20 11:43:00 | Data suggest that most if not all tissues use ZIP8 and ZIP14A/ZIP14B (alternative splicing products) for Zn(2+) uptake, some tissues under basal conditions and others more so when inflammatory stressors are present (as in endotoxemia); collectively, this might lead to substantial alterations in plasma Zn(2+) levels due to Zn(2+) redistribution not just in liver but across many vital organs. | 24728862 |
| Type | IDs |
|---|---|
| Synonymous | 4933419D20Rik, AA986696, BIGM103, ZIP-8, Zip8 |
| Gene |
UniProtKB-ID:
S39A8_MOUSE
UniprotKB:
Q91W10
UniParc:
UPI0000022DE7,
UPI00000EAA56
EMBL:
AK016853,
AK089060,
BC006731,
AK014895,
AK085740
Ensembl:
ENSMUSG00000053897
KO:
mmu:67547
|
| Nucleutide sequences |
EMBL-CDS:
BAB29610.1,
BAB30465.1,
BAC40727.1,
BAC39526.1,
AAH06731.1
Ensembl_TRS:
ENSMUST00000167390,
ENSMUST00000081978,
ENSMUST00000029810,
ENSMUST00000180196
|
| Protein sequencees |
Ensembl_PRO:
ENSMUSP00000080640,
ENSMUSP00000029810,
ENSMUSP00000136634,
ENSMUSP00000128245
RefSeq:
XP_006501999.1,
NP_001128622.1,
XP_006501997.1,
NP_001128621.1,
XP_036019141.1,
NP_080504.3,
XP_006501998.1
|
| Others |
UniRef100:
UniRef100_Q91W10
UniRef90:
UniRef90_Q91W10
UniRef50:
UniRef50_Q9C0K1
UniGene:
Mm.30239,
Mm.491277
CCDS:
CCDS17859.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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