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67544 Fam120b

67544

Fam120b

family with sequence similarity 120, member B

protein-coding

Mus musculus

基因描述

Type Description
Definition family with sequence similarity 120, member B

研究结论

Date Results Publications
2019-01-19 10:46:00 Study report a previously uncharacterized protein, SAN1, the Fam120b gene product, as a 5' exonuclease that acts independently of the Fanconi anemia pathway in response to inter-strand DNA cross-links (ICLs). Deletion of SAN1 in HeLa cells and mouse embryonic fibroblasts causes sensitivity to ICLs. SAN1 binds to senataxin (SETX). SAN1-SETX binding is increased by ICLs and is required to prevent cross-link sensitivity. 29968717
2011-07-23 10:25:00 Sulfonylthiadiazoles with an unusual binding mode were shown as partial dual peroxisome proliferator-activated receptor (PPAR) gamma/delta agonists with high potency and in vivo efficacy. 21400663
2010-01-21 00:00:00 CCPG is a bona fide coactivator and promotes adipogenesis in a PPARgamma-dependent manner. 17595322

名称对应

Type IDs
Synonymous 4932442K08Rik, AW049283, AW413338, CCPG, Pgcc1, mKIAA1838
Gene
UniProtKB-ID: F120B_MOUSE
UniprotKB: Q6RI63
UniParc: UPI00000EA214, UPI00002317C6
EMBL: AK132211, BC085163, AK078215, AK220425, AK050319, DQ873694, AK076185, AK005957, BC003200, AK028911, AY497019
Ensembl: ENSMUSG00000014763
KO: mmu:67544
Nucleutide sequences
EMBL-CDS: BAE21035.1, BAC37177.1, AAH03200.1, BAC26191.1, BAD90470.1, BAC36239.1, ABH09085.1, BAB24339.1, BAC34186.1, AAR30868.1, AAH85163.1
Ensembl_TRS: ENSMUST00000055352
Protein sequencees
Ensembl_PRO: ENSMUSP00000054420
RefSeq: NP_001344751.1, NP_077165.2
Others
UniRef100: UniRef100_Q6RI63
UniRef90: UniRef90_Q6RI63
UniRef50: UniRef50_Q6RI63
UniGene: Mm.35039
CCDS: CCDS37453.1

全选

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