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67512 Agpat2

67512

Agpat2

1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)

protein-coding

Mus musculus

基因描述

Type Description
Definition 1-acylglycerol-3-phosphate O-acyltransferase 2 (lysophosphatidic acid acyltransferase, beta)

研究结论

Date Results Publications
2016-04-09 10:36:00 Adipogenically induced Agpat2(-/-) preadipocytes had fewer lipid-loaded cells and lower levels of adipocyte markers than wild type preadipocytes. 26417690
2014-10-04 11:00:00 Leptin ameliorates insulin resistance and hepatic steatosis in Agpat2-/- lipodystrophic mice independent of hepatocyte leptin receptors 24293639
2014-04-26 12:33:00 The lack of normal insulin signaling in Agpat2(-/-) livers allows unrestricted phosphatidic acid-induced gluconeogenesis. 24425876
2013-01-26 10:39:00 Data suggest that Agpat2 regulates adipogenesis through modulation of lipid metabolism/signal transduction, altering normal activation of phosphatidylinositol 3-kinase (PI3K)/protooncogene c-Akt and PPARgamma signaling in early stage of adipogenesis. 22872237
2011-12-17 11:39:00 the role of AGPAT1 or AGPAT2 in liver lipogenesis is minimal and that accumulation of liver fat is primarily a consequence of insulin resistance 21873652

名称对应

Type IDs
Synonymous 2510002J07Rik, AV000834, BSCL, BSCL1, LPAAB, LPAAT-beta
Gene
UniProtKB-ID: PLCB_MOUSE, Q059U0_MOUSE, Q9CWA8_MOUSE
UniprotKB: Q8K3K7, Q059U0, Q9CWA8
UniParc: UPI0000028A17, UPI00000E6694
EMBL: AY072769, BC137840, AK002422, BC125530
Ensembl: ENSMUSG00000026922
KO: mmu:67512
Nucleutide sequences
EMBL-CDS: AAL62337.1, AAI37841.1, AAI25531.1, BAB22089.1
Ensembl_TRS: ENSMUST00000028286
Protein sequencees
Ensembl_PRO: ENSMUSP00000028286
RefSeq: NP_080488.1, XP_017174711.1
Others
UniRef100: UniRef100_Q8K3K7, UniRef100_Q9CWA8
UniRef90: UniRef90_Q8K3K7, UniRef90_Q9CWA8
UniRef50: UniRef50_Q9CWA8, UniRef50_Q8K3K7
UniGene: Mm.24244
CCDS: CCDS15809.1

全选

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