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67457 Frmd8

67457

Frmd8

FERM domain containing 8

protein-coding

Mus musculus

基因描述

Type Description
Definition FERM domain containing 8

研究结论

Date Results Publications
2019-07-20 10:11:00 results suggest that blood entering the joint activates the iRhom2/ADAM17/TNF-alpha pathway, thereby contributing to osteopenia and synovitis in mice. 29776906
2019-04-20 12:13:00 iTAP (FRMD8) is a novel iRhom2 interactor that controls TNF-alpha secretion by policing the stability of iRhom2/ADAM17 complex. 29897333
2019-04-20 12:13:00 FRMD8 promotes inflammatory and growth factor signaling by stabilizing the iRhom2/ADAM17 sheddase complex. 29897336

名称对应

Type IDs
Synonymous 1200004M23Rik, 2310035N23Rik, 4931429L16Rik, AU018809, iTAP
Gene
UniProtKB-ID: FRMD8_MOUSE
UniprotKB: Q3UFK8
UniParc: UPI000002244C
EMBL: AK049224, BC004765, AK088639, AK148434, AK004603, AK083902, AK011659, AK049233
Ensembl: ENSMUSG00000024816
KO: mmu:67457
Nucleutide sequences
EMBL-CDS: BAC33626.1, BAE28552.1, BAC40471.1, BAB27763.1, BAC33620.1, AAH04765.1, BAC39054.1, BAB23402.1
Ensembl_TRS: ENSMUST00000025728
Protein sequencees
Ensembl_PRO: ENSMUSP00000025728
RefSeq: XP_006531891.1, XP_006531892.1, NP_080445.1
Others
UniRef100: UniRef100_Q3UFK8
UniRef90: UniRef90_Q3UFK8
UniRef50: UniRef50_Q9BZ67-2
UniGene: Mm.202092
CCDS: CCDS29481.1

全选

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