| Type | Description |
|---|---|
| Definition | small RNA binding exonuclease protection factor La |
| Date | Results | Publications |
|---|---|---|
| 2021-03-06 13:28:00 | Functional and Structural Aspects of La Protein Overexpression in Lung Cancer. | 33197462 |
| 2019-08-10 11:23:00 | Data is consistent with human La functioning in translation through contacts to the poly(A) tail. | 29447394 |
| 2019-01-26 12:28:00 | Sumoylation of La protein promotes cell proliferation by averting ubiquitination-mediated degradation of the protein. | 29084811 |
| 2018-02-17 11:08:00 | A cytoplasmic isoform of La protein as well as 6, 4, and 1 function in mRNA metabolism and translation in distinct but similar ways, sometimes with the poly(A)-binding protein, and in some cases by direct binding to poly(A)-RNA. | 28782243 |
| 2018-01-13 13:52:00 | our data support a novel model, whereby cancer-associated La protein contributes to cisplatin resistance by stimulating the translation of anti-apoptotic factor Bcl2 in HNSCC cells. | 27105491 |
| Type | IDs |
|---|---|
| Synonymous | LARP3, La, La/SSB |
| Gene |
UniProtKB-ID:
LA_HUMAN
UniprotKB:
P05455
UniParc:
UPI000012E243
EMBL:
J04205,
AC009967,
CH471058,
BC020818,
X13697,
BT009862,
M20328,
BC001289,
AB451228
Ensembl:
ENSG00000138385
KO:
hsa:6741
|
| Nucleutide sequences |
EMBL-CDS:
EAX11259.1,
AAH20818.1,
AAY14868.1,
BAG70042.1,
AAA51885.1,
AAA36577.1,
CAA31985.1,
AAH01289.1,
AAP88864.1,
EAX11258.1
Ensembl_TRS:
ENST00000409333,
ENST00000260956
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000386636,
ENSP00000260956
RefSeq:
NP_001281074.1,
NP_003133.1
|
| Others |
UniRef100:
UniRef100_P05455
UniRef90:
UniRef90_P05455
UniRef50:
UniRef50_P05455
UniGene:
Hs.632535
CCDS:
CCDS2237.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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