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67405 Nts

67405

Nts

neurotensin

protein-coding

Mus musculus

基因描述

Type Description
Definition neurotensin

研究结论

Date Results Publications
2019-03-02 11:15:00 Study found that locally-released neurotensin (NT) and dynorphin (Dyn) antagonistically regulated central amygdala (CeA) inhibitory inputs onto oval bed nucleus of the stria terminalis (ovBNST) neurons. NT and Dyn respectively increased and decreased CeA-toovBNST inhibitory inputs through NT receptor 1 and kappa opioid receptor. NT and Dyn mRNAs were highly co-localized in ovBNST neurons. 30248304
2018-09-08 10:08:00 Study reveals multiple populations of neurotensin neurons that provide direct afferents to the ventral tegmental area and which may regulate specific aspects of motivated behavior. 29478718
2018-07-28 12:19:00 The weight loss behaviors are mediated by distinct signaling pathways: Nts action via NtsR1 is essential for the anorectic effect of the lateral hypothalamic Nts circuit, but not for regulation of locomotor or drinking behavior. 29241540
2017-10-14 12:50:00 Nts-leptin receptor neurons are important neuronal hubs within the lateral hypothalamic area for hormone-mediated control of ingestive and locomotor behaviors. 28323938
2016-06-28 10:46:00 findings directly link NT with increased fat absorption and obesity and suggest that NT may provide a prognostic marker of future obesity and a potential target for prevention and treatment 27193687

名称对应

Type IDs
Synonymous 5033428E16Rik, NMN-125, NN, NT, NT/N, NTS1
Gene
UniProtKB-ID: NEUT_MOUSE
UniprotKB: Q9D3P9
UniParc: UPI000000B2CB
EMBL: AF348489, AK017212, AF304160, BC043024
Ensembl: ENSMUSG00000019890
KO: mmu:67405
Nucleutide sequences
EMBL-CDS: AAH43024.1, AAK28626.1, AAK15263.1, BAB30636.1
Ensembl_TRS: ENSMUST00000020040
Protein sequencees
Ensembl_PRO: ENSMUSP00000020040
RefSeq: XP_006514055.1, NP_077755.1
Others
UniRef100: UniRef100_Q9D3P9
UniRef90: UniRef90_Q9D3P9
UniRef50: UniRef50_P20068
UniGene: Mm.64201
CCDS: CCDS24154.1

全选

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研究热度

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