| Type | Description |
|---|---|
| Definition | SRSF protein kinase 2 |
| Date | Results | Publications |
|---|---|---|
| 2020-12-05 13:03:00 | Cooperation of SRPK2, Numb and p53 in the malignant biology and chemosensitivity of colorectal cancer. | 31898732 |
| 2020-08-22 15:25:00 | Serine-Arginine SRPK2 Modulates the Assembly of the Active Zone Scaffolding Protein CAST1/ERC2. | 31671734 |
| 2020-05-09 13:40:00 | SRPK2 expression was upregulated in pancreatic cancer tissues, positively correlated with stage, and associated with decreased overall survival in pancreatic cancer patients. In pancreatic cancer cells, SRPK2 overexpression promoted cell invasion and migration, and decreased chemosensitivity to gemcitabine or oxaliplatin. SRPK2 silencing decreased cell invasion and migration and increased chemosensitivity. | 30724469 |
| 2019-05-11 10:16:00 | The conserved SRPK-specific substrate-docking groove in SRPK2 impacts the binding and phosphorylation of both SR proteins, and the localization of SRSF3. | 30478176 |
| 2018-10-06 12:24:00 | SRPK2 may play an important role in the progression and metastasis of prostate cancer. | 29587239 |
| Type | IDs |
|---|---|
| Synonymous | SFRSK2 |
| Gene |
UniProtKB-ID:
SRPK2_HUMAN,
A0A024R704_HUMAN
UniprotKB:
P78362,
A0A024R704
UniParc:
UPI000007420D,
UPI00001A4785
EMBL:
AC005070,
BC035214,
AC073138,
AC004884,
AY354201,
U88666,
BC068547,
BE781215,
CH471070
Ensembl:
ENSG00000135250
KO:
hsa:6733
|
| Nucleutide sequences |
EMBL-CDS:
EAW83359.1,
AAC05299.1,
AAC29140.1,
AAH35214.1,
AAC29141.1,
AAQ63886.1,
AAH68547.1,
EAW83360.1,
EAW83361.1
Gene_ORFName:
hCG_2013856
Ensembl_TRS:
ENST00000393651,
ENST00000489828,
ENST00000357311
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000377262,
ENSP00000419791,
ENSP00000349863
RefSeq:
NP_872634.1,
NP_001337669.1,
NP_001337667.1,
NP_001337674.1,
NP_001337668.1,
XP_024302662.1,
NP_001337675.1,
XP_006716161.1,
NP_001265202.1,
XP_011514838.1,
XP_016868050.2,
XP_024302661.1,
NP_001337672.1,
NP_001337670.1,
NP_001337673.1,
XP_024302663.1,
NP_001337671.1,
XP_011514840.1,
NP_872633.1
|
| Others |
UniRef100:
UniRef100_P78362
UniRef90:
UniRef90_P78362
UniRef50:
UniRef50_P78362
UniGene:
Hs.285197
CCDS:
CCDS34724.1,
CCDS5735.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
{{aff.value}} |
{{aff.size}} |
目前还没有研究热点单位
| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
{{author.value}} |
{{author.size}} |
目前还没有研究热点人员