| Type | Description |
|---|---|
| Definition | CD99 antigen |
| Date | Results | Publications |
|---|---|---|
| 2020-02-08 12:06:00 | Upon neutrophil arrest, binding of PILR-beta1 to CD99 ceases, shifting the signaling balance towards inhibitory PILR-alpha. This enables integrin deactivation and supports cell diapedesis in venules of the mouse cremaster muscle. | 31385804 |
| 2017-08-26 13:10:00 | endothelial CD99 promotes leukocyte attachment to endothelium in inflamed vessels by a heterophilic ligand. In addition, CD99 binds to PILRs on neutrophils, an interaction that leads to increased shear resistance of the neutrophil attachment to ICAM-1. | 28223280 |
| 2015-09-12 11:10:00 | Endothelial CD99 signals through soluble adenylyl cyclase and to regulate leukocyte transendothelial migration. | 26101266 |
| 2014-02-22 11:38:00 | role in membrane trafficking of CD99L2 and in controlling transendothelial migration of leukocytes | 24133166 |
| 2012-07-14 10:34:00 | CD99 plays a crucial role in the attenuation of graft-versus-host disease by regulating the expansion of myeloid-derived suppressor cells. | 22350746 |
| Type | IDs |
|---|---|
| Synonymous | 1110061M03Rik, 2410026K10Rik, D4, Pilr-l, pilr-1 |
| Gene |
UniProtKB-ID:
CD99_MOUSE
UniprotKB:
Q8VCN6
UniParc:
UPI000002897A
EMBL:
AK044051,
AY262359,
BC019482,
AY262355
KO:
mmu:673094
|
| Nucleutide sequences |
EMBL-CDS:
BAC31754.1,
AAP91691.1,
AAP91687.1,
AAH19482.1
|
| Protein sequencees |
RefSeq:
NP_079860.2
|
| Others |
UniRef100:
UniRef100_Q8VCN6
UniRef90:
UniRef90_Q8VCN6
UniRef50:
UniRef50_Q8VCN6
UniGene:
Mm.423040
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
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| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
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