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67260 Cers4

67260

Cers4

ceramide synthase 4

protein-coding

Mus musculus

基因描述

Type Description
Definition ceramide synthase 4

研究结论

Date Results Publications
2016-08-20 10:23:00 These results suggest that the phosphorylation of ceramide synthases may be a key regulatory point in the control of the distribution and levels of sphingolipids of various acyl-chain lengths. 26887952
2015-08-01 10:24:00 CerS4-directed epidermal ceramide composition is essential to control hair follicle stem and progenitor cell behavior potentially through its regulation of BMP and Wnt signaling 25705848
2014-08-16 10:41:00 Loss of CerS4 protein leads to an altered lipid composition of the sebum, which is more solidified and therefore might cause progressive hair loss due to physical blocking of the hair canal. 24738593
2014-04-26 10:14:00 Data indicate that oxidized phospholipids (OxPLs)-induced ceramide synthases (CerS1-Cers6) activity in macrophages is responsible for the accumulation of ceramide. 23936132
2010-01-21 00:00:00 Lag1p family members trh1 and trh4 regulate (dihydro)ceramide synthases responsible for production of sphingolipids containing different fatty acids 12912983

名称对应

Type IDs
Synonymous 2900019C14Rik, Lass4, Trh1
Gene
UniProtKB-ID: CERS4_MOUSE
UniprotKB: Q9D6J1
UniParc: UPI000002718F
EMBL: AY029531, AK030280, AK028945, BC003946, AK013554, AK021316, AK028937
Ensembl: ENSMUSG00000008206
KO: mmu:67260
Nucleutide sequences
EMBL-CDS: BAC26202.1, AAH03946.1, AAK40299.1, BAB28903.1, BAC26876.1, BAB32370.3, BAC26208.1
Ensembl_TRS: ENSMUST00000008350
Protein sequencees
Ensembl_PRO: ENSMUSP00000008350
RefSeq: XP_006508925.1, NP_080334.3, XP_030099592.1, XP_036010142.1, XP_006508926.1, XP_006508924.1
Others
UniRef100: UniRef100_Q9D6J1
UniRef90: UniRef90_Q9D6J1
UniRef50: UniRef50_Q9D6J1
UniGene: Mm.35511
CCDS: CCDS22086.1

全选

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