| Type | Description |
|---|---|
| Definition | src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites |
| Date | Results | Publications |
|---|---|---|
| 2019-03-09 12:21:00 | Vimentin and Sam68, are identified as bona fide SRMS substrates through in vitro and in vivo assays. | 29496907 |
| 2015-10-03 10:31:00 | SRMS phosphorylated the C terminus of BRK, but not SRC. | 25897081 |
| 2013-10-26 12:40:00 | The unique N-terminal region of SRMS regulates enzymatic activity and phosphorylation of its novel substrate docking protein 1. | 23822091 |
| Type | IDs |
|---|---|
| Synonymous | C20orf148, PTK70, SRM, dJ697K14.1 |
| Gene |
UniProtKB-ID:
SRMS_HUMAN
UniprotKB:
Q9H3Y6
UniParc:
UPI000004F1F3
EMBL:
AL121829
Ensembl:
ENSG00000125508
KO:
hsa:6725
|
| Nucleutide sequences |
Ensembl_TRS:
ENST00000217188
|
| Protein sequencees |
Ensembl_PRO:
ENSP00000217188
RefSeq:
NP_543013.1
|
| Others |
UniRef100:
UniRef100_Q9H3Y6
UniRef90:
UniRef90_Q9H3Y6
UniRef50:
UniRef50_Q9H3Y6
UniGene:
Hs.411061
CCDS:
CCDS13525.1
|
| {{proteinIndex+1}} | mRNA | Protein | UniprotKB | Description | ||||
|---|---|---|---|---|---|---|---|---|
| Refseq |
{{protein.nucleotideVersion}}
Ensembl: {{protein.nucleotideEnsembl}} |
{{protein.proteinVersion}}
Ensembl: {{protein.proteinEnsembl}} |
{{uniprot}} , |
Definition: {{{protein.definition}}}Transcript Veriant:{{protein.transcriptVeriant}} Status: {{protein.status}} |
||||
| Location | {{protein.contigId}} ( {{protein.positionStart}}..{{protein.positionEnd}} , {{protein.orientation}} ) | |||||||
| Conserved domain | Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
Region: {{conservedDomain.region == '' || conservedDomain.region == null ? "-": conservedDomain.region}} GFID: {{conservedDomain.gfid == '' || conservedDomain.gfid == null ? "-": conservedDomain.gfid}} Family: {{conservedDomain.family == '' || conservedDomain.family == null ? "-": conservedDomain.family}} CDD: {{conservedDomain.cdd}} - |
{{conservedDomain.comments == '' || conservedDomain.comments == null ? "-" : conservedDomain.comments }} |
||||
暂无数据
| Pubmed编号 | 文献信息 | 发表日期 | 相关基因 |
|---|---|---|---|
| 32296183 |
A reference map of the human binary protein interactome. Nature Katja Luck , Dae-Kyum Kim , Luke Lambourne , Kerstin Spirohn , Bridget E Begg , Wenting Bian , Ruth Brignall , Tiziana Cafarelli , Francisco J Campos-Laborie , Benoit Charloteaux , Dongsic Choi , Atina G Coté , Meaghan Daley , Steven Deimling , Alice Desbuleux , Amélie Dricot , Marinella Gebbia , Madeleine F Hardy , Nishka Kishore , Jennifer J Knapp , István A Kovács , Irma Lemmens , Miles W Mee , Joseph C Mellor , Carl Pollis , Carles Pons , Aaron D Richardson , Sadie Schlabach , Bridget Teeking , Anupama Yadav , Mariana Babor , Dawit Balcha , Omer Basha , Christian Bowman-Colin , Suet-Feung Chin , Soon Gang Choi , Claudia Colabella , Georges Coppin , Cassandra D'Amata , David De Ridder , Steffi De Rouck , Miquel Duran-Frigola , Hanane Ennajdaoui , Florian Goebels , Liana Goehring , Anjali Gopal , Ghazal Haddad , Elodie Hatchi , Mohamed Helmy , Yves Jacob , Yoseph Kassa , Serena Landini , Roujia Li , Natascha van Lieshout , Andrew MacWilliams , Dylan Markey , Joseph N Paulson , Sudharshan Rangarajan , John Rasla , Ashyad Rayhan , Thomas Rolland , Adriana San-Miguel , Yun Shen , Dayag Sheykhkarimli , Gloria M Sheynkman , Eyal Simonovsky , Murat TaÅan , Alexander Tejeda , Vincent Tropepe , Jean-Claude Twizere , Yang Wang , Robert J Weatheritt , Jochen Weile , Yu Xia , Xinping Yang , Esti Yeger-Lotem , Quan Zhong , Patrick Aloy , Gary D Bader , Javier De Las Rivas , Suzanne Gaudet , Tong Hao , Janusz Rak , Jan Tavernier , David E Hill , Marc Vidal , Frederick P Roth , Michael A Calderwood |
2020-04-01 | - |
| 30515972 |
J Cell Mol Med Ting Zhu , Shu An , Man-Ting Choy , Junhao Zhou , Shanshan Wu , Shihua Liu , Bangdong Liu , Zhicheng Yao , Xun Zhu , Jueheng Wu , Zhenjian He |
2019-03-01 | - |
| 29496907 |
Mol Cell Proteomics Raghuveera Kumar Goel , Marta Paczkowska , Jüri Reimand , Scott Napper , Kiven Erique Lukong |
2018-05-01 | - |
| 29568343 |
The SRC-family tyrosine kinase HCK shapes the landscape of SKAP2 interactome. Oncotarget Jean-François Bureau , Patricia Cassonnet , Laura Grange , Julien Dessapt , Louis Jones , Caroline Demeret , Anavaj Sakuntabhai , Yves Jacob |
2018-03-02 | - |
| 25897081 |
Protein-tyrosine Phosphatase and Kinase Specificity in Regulation of SRC and Breast Tumor Kinase. J Biol Chem Gaofeng Fan , Saadat Aleem , Ming Yang , W Todd Miller , Nicholas K Tonks |
2015-06-26 | - |
| 25852190 |
Sci Signal Jonathan So , Adrian Pasculescu , Anna Y Dai , Kelly Williton , Andrew James , Vivian Nguyen , Pau Creixell , Erwin M Schoof , John Sinclair , Miriam Barrios-Rodiles , Jun Gu , Aldis Krizus , Ryan Williams , Marina Olhovsky , James W Dennis , Jeffrey L Wrana , Rune Linding , Claus Jorgensen , Tony Pawson , Karen Colwill |
2015-04-07 | - |
| 23822091 |
FEBS J. Raghuveera K Goel , Sayem Miah , Kristin Black , Natasha Kalra , Chenlu Dai , Kiven E Lukong |
2013-09-01 |
Srms,
DOK1,
SRMS
|
| 23535732 |
Nat Genet Rosalind A Eeles , Ali Amin Al Olama , Sara Benlloch , Edward J Saunders , Daniel A Leongamornlert , Malgorzata Tymrakiewicz , Maya Ghoussaini , Craig Luccarini , Joe Dennis , Sarah Jugurnauth-Little , Tokhir Dadaev , David E Neal , Freddie C Hamdy , Jenny L Donovan , Ken Muir , Graham G Giles , Gianluca Severi , Fredrik Wiklund , Henrik Gronberg , Christopher A Haiman , Fredrick Schumacher , Brian E Henderson , Loic Le Marchand , Sara Lindstrom , Peter Kraft , David J Hunter , Susan Gapstur , Stephen J Chanock , Sonja I Berndt , Demetrius Albanes , Gerald Andriole , Johanna Schleutker , Maren Weischer , Federico Canzian , Elio Riboli , Tim J Key , Ruth C Travis , Daniele Campa , Sue A Ingles , Esther M John , Richard B Hayes , Paul D P Pharoah , Nora Pashayan , Kay-Tee Khaw , Janet L Stanford , Elaine A Ostrander , Lisa B Signorello , Stephen N Thibodeau , Dan Schaid , Christiane Maier , Walther Vogel , Adam S Kibel , Cezary Cybulski , Jan Lubinski , Lisa Cannon-Albright , Hermann Brenner , Jong Y Park , Radka Kaneva , Jyotsna Batra , Amanda B Spurdle , Judith A Clements , Manuel R Teixeira , Ed Dicks , Andrew Lee , Alison M Dunning , Caroline Baynes , Don Conroy , Melanie J Maranian , Shahana Ahmed , Koveela Govindasami , Michelle Guy , Rosemary A Wilkinson , Emma J Sawyer , Angela Morgan , David P Dearnaley , Alan Horwich , Robert A Huddart , Vincent S Khoo , Christopher C Parker , Nicholas J Van As , Christopher J Woodhouse , Alan Thompson , Tim Dudderidge , Chris Ogden , Colin S Cooper , Artitaya Lophatananon , Angela Cox , Melissa C Southey , John L Hopper , Dallas R English , Markus Aly , Jan Adolfsson , Jiangfeng Xu , Siqun L Zheng , Meredith Yeager , Rudolf Kaaks , W Ryan Diver , Mia M Gaudet , Mariana C Stern , Roman Corral , Amit D Joshi , Ahva Shahabi , Tiina Wahlfors , Teuvo L J Tammela , Anssi Auvinen , Jarmo Virtamo , Peter Klarskov , Børge G Nordestgaard , M Andreas Røder , Sune F Nielsen , Stig E Bojesen , Afshan Siddiq , Liesel M Fitzgerald , Suzanne Kolb , Erika M Kwon , Danielle M Karyadi , William J Blot , Wei Zheng , Qiuyin Cai , Shannon K McDonnell , Antje E Rinckleb , Bettina Drake , Graham Colditz , Dominika Wokolorczyk , Robert A Stephenson , Craig Teerlink , Heiko Muller , Dietrich Rothenbacher , Thomas A Sellers , Hui-Yi Lin , Chavdar Slavov , Vanio Mitev , Felicity Lose , Srilakshmi Srinivasan , Sofia Maia , Paula Paulo , Ethan Lange , Kathleen A Cooney , Antonis C Antoniou , Daniel Vincent , François Bacot , Daniel C Tessier , COGSâCancer Research UK GWASâELLIPSE (part of GAME-ON) Initiative , Australian Prostate Cancer Bioresource , UK Genetic Prostate Cancer Study Collaborators/British Association of Urological Surgeons' Section of Oncology , UK ProtecT (Prostate testing for cancer and Treatment) Study Collaborators , PRACTICAL (Prostate Cancer Association Group to Investigate Cancer-Associated Alterations in the Genome) Consortium , Zsofia Kote-Jarai , Douglas F Easton |
2013-04-01 | - |
| 21873635 |
Phylogenetic-based propagation of functional annotations within the Gene Ontology consortium. Brief. Bioinformatics Pascale Gaudet , Michael S Livstone , Suzanna E Lewis , Paul D Thomas |
2011-09-01 | - |
| 19953087 |
Mol. Syst. Biol. Avinash Persaud , Philipp Alberts , Eva M Amsen , Xuejian Xiong , James Wasmuth , Zachary Saadon , Chris Fladd , John Parkinson , Daniela Rotin |
2009-01-01 |
Nedd4,
Nedd4l,
Acvr1b,
Cacnb1,
AKT3,
TOM1,
SGK2,
CDK3,
CDK5,
UBAC1,
BAIAP2,
MERTK,
STK25,
SIVA1,
RBCK1,
RAD51AP1,
CAMKK2,
MAP3K2,
PLK2,
SEPT9,
MAP4K5,
PRRT2,
SAAL1,
CLIC2,
CLK3,
MOB3A,
GRK7,
MAP3K8,
SPANXN3,
TCP10L,
TCEAL2,
CSNK2A1,
BEAN1,
TOM1L2,
DIRAS1,
GRK2,
DAPK3,
TCEANC,
ACAN,
EGFR,
EIF5,
MARK2,
DMTN,
EPHA5,
AKT1,
RASGEF1A,
FES,
FGF12,
FGFR1,
FGFR2,
FKBP3,
UBOX5,
RTF1,
FLT1,
SULF1,
FLT4,
NEDD4L,
WBP2,
ABL1,
FYN,
DECR2,
SPAG8,
FGF21,
GBA,
TIMM10,
RNF11,
AMPD2,
ABL2,
APEX2,
ZADH2,
GRK4,
TBK1,
EFEMP2,
H1F0,
SERPIND1,
ANKRD13D,
AQP9,
IRS1,
KCNB1,
KIFC3,
CUEDC1,
SMAD3,
MAGEB1,
MAP2,
MAP3K3,
MAP3K5,
NEDD4,
NTRK1,
NTRK2,
MINK1,
TBC1D7,
ZDHHC3,
PRR16,
PDGFRA,
PDGFRB,
LUC7L2,
SERPINF1,
STK26,
ZAK
|
| 排名 | 科研单位 | 文献 |
|---|---|---|
| {{affIndex+1}} |
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| 排名 | 研究人员 | 文献 |
|---|---|---|
| {{authorIndex+1}} |
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